Conversion of antibacterial activity of graphene-coated textiles through surface polarity

Daniela P. Rodrigues; Catarina Moreirinha; Gopika Rajan; Ana I.S. Neves; Sidónio C. Freitas; Sara Sequeira; Saverio Russo; Monica F. Craciun; Adelaide Almeida; Helena Alves

doi:10.1002/nano.202100226

Conversion of antibacterial activity of graphene-coated textiles through surface polarity

Daniela P. Rodrigues, Catarina Moreirinha, Gopika Rajan, Ana I.S. Neves, Sidónio C. Freitas, Sara Sequeira, Saverio Russo, Monica F. Craciun (Corresponding author), Adelaide Almeida, Helena Alves (Corresponding author)

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Abstract Graphene is emerging in numerous wearable and biomedical applications. Understanding the impact of graphene-based nanocomposites over bacterial activity is critical for design appropriate technical solutions. In this work, antibacterial activity of monolayer and few-layer graphene is tested against Gram-negative and Gram-positive model bacteria. Such graphene-based nanomaterials present different effects on bacteria viability, depending on concentration and shape. The presence of dopant agents can either increase or revert graphene antibacterial effect. Among other bactericidal mechanisms, we also demonstrate that graphene surface polarity is connected to antibacterial properties and can be easily modified by surface charge transfer doping. This electrophilicity tuning offers a novel mechanism for the molecular basis of graphene's antibacterial activity.

Original language	English
Pages (from-to)	502-512
Number of pages	11
Journal	Nano Select
Volume	4
Issue number	8
DOIs	https://doi.org/10.1002/nano.202100226
Publication status	Published - Aug 2023
Externally published	Yes

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title = "Conversion of antibacterial activity of graphene-coated textiles through surface polarity",

abstract = "Abstract Graphene is emerging in numerous wearable and biomedical applications. Understanding the impact of graphene-based nanocomposites over bacterial activity is critical for design appropriate technical solutions. In this work, antibacterial activity of monolayer and few-layer graphene is tested against Gram-negative and Gram-positive model bacteria. Such graphene-based nanomaterials present different effects on bacteria viability, depending on concentration and shape. The presence of dopant agents can either increase or revert graphene antibacterial effect. Among other bactericidal mechanisms, we also demonstrate that graphene surface polarity is connected to antibacterial properties and can be easily modified by surface charge transfer doping. This electrophilicity tuning offers a novel mechanism for the molecular basis of graphene's antibacterial activity.",

keywords = "antimicrobial surfaces, bacterial activity, graphene, smart textiles, surface charge transfer doping",

author = "Rodrigues, {Daniela P.} and Catarina Moreirinha and Gopika Rajan and Neves, {Ana I.S.} and Freitas, {Sid{\'o}nio C.} and Sara Sequeira and Saverio Russo and Craciun, {Monica F.} and Adelaide Almeida and Helena Alves",

year = "2023",

month = aug,

doi = "10.1002/nano.202100226",

language = "English",

volume = "4",

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journal = "Nano Select",

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TY - JOUR

T1 - Conversion of antibacterial activity of graphene-coated textiles through surface polarity

AU - Rodrigues, Daniela P.

AU - Moreirinha, Catarina

AU - Rajan, Gopika

AU - Neves, Ana I.S.

AU - Freitas, Sidónio C.

AU - Sequeira, Sara

AU - Russo, Saverio

AU - Craciun, Monica F.

AU - Almeida, Adelaide

AU - Alves, Helena

PY - 2023/8

Y1 - 2023/8

N2 - Abstract Graphene is emerging in numerous wearable and biomedical applications. Understanding the impact of graphene-based nanocomposites over bacterial activity is critical for design appropriate technical solutions. In this work, antibacterial activity of monolayer and few-layer graphene is tested against Gram-negative and Gram-positive model bacteria. Such graphene-based nanomaterials present different effects on bacteria viability, depending on concentration and shape. The presence of dopant agents can either increase or revert graphene antibacterial effect. Among other bactericidal mechanisms, we also demonstrate that graphene surface polarity is connected to antibacterial properties and can be easily modified by surface charge transfer doping. This electrophilicity tuning offers a novel mechanism for the molecular basis of graphene's antibacterial activity.

AB - Abstract Graphene is emerging in numerous wearable and biomedical applications. Understanding the impact of graphene-based nanocomposites over bacterial activity is critical for design appropriate technical solutions. In this work, antibacterial activity of monolayer and few-layer graphene is tested against Gram-negative and Gram-positive model bacteria. Such graphene-based nanomaterials present different effects on bacteria viability, depending on concentration and shape. The presence of dopant agents can either increase or revert graphene antibacterial effect. Among other bactericidal mechanisms, we also demonstrate that graphene surface polarity is connected to antibacterial properties and can be easily modified by surface charge transfer doping. This electrophilicity tuning offers a novel mechanism for the molecular basis of graphene's antibacterial activity.

KW - antimicrobial surfaces

KW - bacterial activity

KW - graphene

KW - smart textiles

KW - surface charge transfer doping

U2 - 10.1002/nano.202100226

DO - 10.1002/nano.202100226

M3 - Article

SN - 2688-4011

VL - 4

SP - 502

EP - 512

JO - Nano Select

JF - Nano Select

IS - 8

ER -

Conversion of antibacterial activity of graphene-coated textiles through surface polarity

Abstract

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