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Constructing level-2 phylogenetic networks from triplets

  • L.J.J. Iersel, van
  • , J.C.M. Keijsper
  • , S.M. Kelk
  • , L. Stougie
  • , F. Hagen
  • , T. Boekhout

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Abstract

Jansson and Sung showed that, given a dense set of input triplets T (representing hypotheses about the local evolutionary relationships of triplets of taxa), it is possible to determine in polynomial time whether there exists a level-1 network consistent with T, and if so to construct such a network [18]. Here we extend this work by showing that this problem is even polynomial-time solvable for the construction of level-2 networks. This shows that, assuming density, it is tractable to construct plausible evolutionary histories from input triplets even when such histories are heavily non-tree like. This further strengthens the case for the use of triplet-based methods in the construction of phylogenetic networks. We also implemented the algorithm and applied it to yeast data. Part of this research has been funded by the Dutch BSIK/BRICKS project.
Original languageEnglish
Title of host publicationResearch in Computational Molecular Biology (Proceedings 12th Annual International Conference, RECOMB 2008, Singapore, March 30-April 2, 2008)
EditorsM. Vingron, L. Wong
Place of PublicationBerlin
PublisherSpringer
Pages450-462
ISBN (Print)978-3-540-78838-6
DOIs
Publication statusPublished - 2008

Publication series

NameLecture Notes in Computer Science
Volume4955
ISSN (Print)0302-9743

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