Conformational analysis of dipeptide derived polyisocyanides

J.J.L.M. Cornelissen, W.S. Graswinckel, A.E. Rowan, N.A.J.M. Sommerdijk, R.J.M. Nolte

Research output: Contribution to journalArticleAcademicpeer-review

49 Citations (Scopus)


The conformational properties of polymers derived from isocyanodipeptides have been investigated with a combination of model calculations, X-ray diffraction, and circular dichroism spectroscopy. Depending on the configuration of the side chains, defined arrays of hydrogen bonds along the polymeric backbone are formed. This leads to a well-defined conformation as, for example, expressed in the formation of lyotropic liquid-crystalline phases and increased helical stability. Upon the disruption of the hydrogen bonds by a strong acid, a less well-defined macromolecular conformation is observed
Original languageEnglish
Pages (from-to)1725-1736
JournalJournal of Polymer Science, Part A: Polymer Chemistry
Issue number11
Publication statusPublished - 2003


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