Computer control versus manual control of systemic hypertension during cardiac surgery

S.A.A.P. Hoeksel, J.A. Blom, J.R.C. Jansen, J.G. Maessen, J.J. Schreuder

Research output: Contribution to journalArticleAcademicpeer-review

12 Citations (Scopus)
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Abstract

Keywords:Cardiac surgery;hypertension;closed-loop controlBackground: We recently demonstrated the feasibility of computer controlled infusion of vasoactive drugs for the control of systemic hypertension during cardiac surgery. The objective of the current study was to investigate the effects of computer controlled blood pressures on hemodynamic stability when compared to conventional manual control. Method: Systemic artery blood pressures were managed either by computer (80 patients) or by a well-trained anesthesiologist (80 patients). The vasodilator drugs sodium nitroprusside and nitroglycerin were used. Hemodynamic stability was determined from the standard deviation of the mean arterial pressure samples and from the percentages of time that arterial pressure was hypertensive or hypotensive. Results: The average standard deviation of the mean arterial pressure samples was smaller for the computer controlled than for the manually controlled group: 7.5±2.2 (mean±SD) versus 8.9±2.3 mmHg (P
Original languageEnglish
Pages (from-to)553-557
Number of pages5
JournalActa Anaesthesiologica Scandinavica
Volume45
Issue number5
DOIs
Publication statusPublished - 2001

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