TY - JOUR
T1 - Computational simulation of migration and dispersion in free capillary zone electrophoresis, II: Results of simulation and comparison with measurements
AU - Reijenga, J.C.
AU - Kenndler, E.
PY - 1994
Y1 - 1994
N2 - The results of the simulation of electropherograms for CZE obtained by the instrumental simulator described in Part I are presented as functions of various experimental parameters. The electropherograms, demonstrating the effects of the injection zone length and sample composition on peak broadening, of the potential on migration and efficiency, of minute changes in pH on the resolution, of the ionic strength of the buffer on the separation selectivity and of the co-ion of the background electrolyte on peak shape, are simulated within a few seconds. A comparison was made between simulated electropherograms and those obtained by measurements with real equipment.
AB - The results of the simulation of electropherograms for CZE obtained by the instrumental simulator described in Part I are presented as functions of various experimental parameters. The electropherograms, demonstrating the effects of the injection zone length and sample composition on peak broadening, of the potential on migration and efficiency, of minute changes in pH on the resolution, of the ionic strength of the buffer on the separation selectivity and of the co-ion of the background electrolyte on peak shape, are simulated within a few seconds. A comparison was made between simulated electropherograms and those obtained by measurements with real equipment.
U2 - 10.1016/0021-9673(94)85084-4
DO - 10.1016/0021-9673(94)85084-4
M3 - Article
SN - 0021-9673
VL - 659
SP - 417
EP - 426
JO - Journal of Chromatography, A
JF - Journal of Chromatography, A
IS - 2
ER -