Composition of the nucleotide pool in a morphogenetic compartment in eggs of nassarius reticulatus (mollusca) analyzed by capillary isotachphoresis

C.A.M. Dongen, van, J.H. Wes, J.H. Goedemans, J.C. Reijenga

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Abstract

The spectrum of low molecular weight compounds, in particular of ribonucleotides, within first cleavage stage embryos of the polar lobe-forming mollusc Nassarius reticulatus and the distribution of the compounds within the embryo at the trefoil stage of first cleavage are analysed by means of capillary isotachophoresis after 0.5 M PCA extraction. The compounds which are found in the whole trefoil embryo (T), the lobeless part (LL), and the polar lobe (PL) respectively, and the mean quantities (nmol. µl-1; n=6) are: UTP (11.5, 4.8, 5.6), ITP (8.5, 3.6, 5.0), GTP (10.3, 3.0, 9.0), ATP (29.8, 13.4, 18.8), UDP (11.8, 3.4, 8.7), CTP (8.0, 3.1, 4.5), GDP (5.3, 2.6, 3.4), ADP(16.5, 6.1, 11.6), CDP(4.0, 1.4, 2.6), GMP (4.7, 2.7,4.3), glucose-6-phosphate (G6P) (53.5, 38.8, 13.0). These compounds appear to be localized in the non-yolk cytoplasmic pool. As the volume ratio of PL/LL for total volume and for non-yolk cytoplasmic volume is about 0.74 and 0.60 respectively, the concentration of all nucleotides in PL as compared to LL is significantly higher (HO, p
Original languageEnglish
Pages (from-to)406-420
JournalExperimental Cell Research
Volume161
Issue number2
DOIs
Publication statusPublished - 1985

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