Combining volume clamp blood pressure measurement and pulse oximetry

G.G.H. Claassen

    Research output: ThesisPd Eng Thesis


    This report covers the work of a one year project presented to Eindhoven University of Technology towards the degree of Professional Doctorate in Engineering in Design and Technology of Instrumentation.
    The project is performed at, and in request of, the Amsterdam department of Edwards Lifesciences. Edwards Lifesciences is the global leader in patient-focused medical innovations for structural heart disease, as well as Critical Care and Surgical Monitoring. Driven by a passion to help patients, the company collaborates with the world’s leading clinicians and researchers to address unmet healthcare needs, working to improve patient outcomes and enhance lives.
    The Amsterdam office, known as Edwards Lifesciences BMEYE, was a spin-off from TNO that developed volume clamp blood pressure measurement devices (Nexfin). BMEYE was acquired by Edwards Lifesciences in 2012. Now the Amsterdam office is in transition to become an early stage research and development department of Edwards Lifesciences, mainly regarding non-invasive blood pressure measurement.
    Edwards Lifesciences is dedicated, not only to providing new innovative solutions, but also to strengthening its core by keep improving their current technologies. This project is executed in that mindset.
    During the project basic principles regarding the volume clamp technology were further investigated. This involved diving deep into multi-spectral light-tissue interaction, research and design of finger cuffs and development of photo-plethysmography measurement devices.
    The measurement results is where literature, physiology and design parameters come together. This is where the need for structured data analysis and clarifying visualization arises to gain knowledge from this complex material.
    Original languageEnglish
    Awarding Institution
    • van Goudoever, Jeroen, External supervisor, External person
    • van Leeuwen, K.A.H., Supervisor
    • Cottaar, E.J.E. (Ward), Supervisor
    Award date8 Dec 2016
    Place of PublicationEindhoven
    Print ISBNs978-90-444-1460-8
    Publication statusPublished - 8 Dec 2016

    Bibliographical note



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