Cognition and quality of life in patients with poststroke epilepsy: a case–control study

J.H. van Tuijl, E.P.M. van Raak, R.J. van Oostenbrugge, A.P. Aldenkamp, R.P.W. Rouhl (Corresponding author)

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Introduction: Though seizures are a common complication after stroke, only little scientific evidence is available about the impact of epilepsy on cognitive functioning and quality of life in patients who have had a stroke. Therefore, we assessed these items in a case–control study. Methods: We studied 36 patients with poststroke epilepsy (PSE) and 36 matched patients who have had a stroke without epilepsy using parts of the FePsy (the computerized visual searching task (CVST) for central information processing speed and a reaction time test), the mini-mental-state examination (MMSE), the EuroQol, the stroke-adapted Sickness Impact Profile questionnaire (SA-SIP-30), the Barthel index, the modified Rankin scale, and the National Institutes of Health stroke scale (NIHSS). Results: Patients with PSE had significantly lower scores on the CVST and MMSE. Generic quality of life was the same in patients with poststroke epilepsy and patients with stroke only, however, the SA-SIP-30 showed a lower disease-specific quality of life in patients with poststroke epilepsy. The Barthel index showed no difference between both groups, but both the modified Rankin scale and the NIHSS were significantly higher in patients with poststroke epilepsy, indicating more disability and neurological impairment in patients with PSE. Conclusions: We found that PSE relates to impaired cognitive functioning, a lower disease-specific quality of life and more disability and neurological impairment. This underlines the importance of further clinical research in this field. This article is part of the Special Issue “Seizures & Stroke”

LanguageEnglish
Article number106444
JournalEpilepsy and Behavior
DOIs
StateE-pub ahead of print - 30 Aug 2019

Fingerprint

Cognition
Case-Control Studies
Epilepsy
Quality of Life
Stroke
National Institutes of Health (U.S.)
Seizures
Sickness Impact Profile
Intelligence Tests
Automatic Data Processing
Reaction Time
Research

Keywords

  • Cognitive function
  • Poststroke epilepsy
  • Quality of life
  • Seizure
  • Stroke

Cite this

van Tuijl, J. H., van Raak, E. P. M., van Oostenbrugge, R. J., Aldenkamp, A. P., & Rouhl, R. P. W. (2019). Cognition and quality of life in patients with poststroke epilepsy: a case–control study. Epilepsy and Behavior, [106444]. DOI: 10.1016/j.yebeh.2019.106444
van Tuijl, J.H. ; van Raak, E.P.M. ; van Oostenbrugge, R.J. ; Aldenkamp, A.P. ; Rouhl, R.P.W./ Cognition and quality of life in patients with poststroke epilepsy : a case–control study. In: Epilepsy and Behavior. 2019
@article{d59d6ac635bb4ddfbfb502b969de33af,
title = "Cognition and quality of life in patients with poststroke epilepsy: a case–control study",
abstract = "Introduction: Though seizures are a common complication after stroke, only little scientific evidence is available about the impact of epilepsy on cognitive functioning and quality of life in patients who have had a stroke. Therefore, we assessed these items in a case–control study. Methods: We studied 36 patients with poststroke epilepsy (PSE) and 36 matched patients who have had a stroke without epilepsy using parts of the FePsy (the computerized visual searching task (CVST) for central information processing speed and a reaction time test), the mini-mental-state examination (MMSE), the EuroQol, the stroke-adapted Sickness Impact Profile questionnaire (SA-SIP-30), the Barthel index, the modified Rankin scale, and the National Institutes of Health stroke scale (NIHSS). Results: Patients with PSE had significantly lower scores on the CVST and MMSE. Generic quality of life was the same in patients with poststroke epilepsy and patients with stroke only, however, the SA-SIP-30 showed a lower disease-specific quality of life in patients with poststroke epilepsy. The Barthel index showed no difference between both groups, but both the modified Rankin scale and the NIHSS were significantly higher in patients with poststroke epilepsy, indicating more disability and neurological impairment in patients with PSE. Conclusions: We found that PSE relates to impaired cognitive functioning, a lower disease-specific quality of life and more disability and neurological impairment. This underlines the importance of further clinical research in this field. This article is part of the Special Issue “Seizures & Stroke”",
keywords = "Cognitive function, Poststroke epilepsy, Quality of life, Seizure, Stroke",
author = "{van Tuijl}, J.H. and {van Raak}, E.P.M. and {van Oostenbrugge}, R.J. and A.P. Aldenkamp and R.P.W. Rouhl",
year = "2019",
month = "8",
day = "30",
doi = "10.1016/j.yebeh.2019.106444",
language = "English",
journal = "Epilepsy and Behavior",
issn = "1525-5050",
publisher = "Academic Press Inc.",

}

Cognition and quality of life in patients with poststroke epilepsy : a case–control study. / van Tuijl, J.H.; van Raak, E.P.M.; van Oostenbrugge, R.J.; Aldenkamp, A.P.; Rouhl, R.P.W. (Corresponding author).

In: Epilepsy and Behavior, 30.08.2019.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Cognition and quality of life in patients with poststroke epilepsy

T2 - Epilepsy and Behavior

AU - van Tuijl,J.H.

AU - van Raak,E.P.M.

AU - van Oostenbrugge,R.J.

AU - Aldenkamp,A.P.

AU - Rouhl,R.P.W.

PY - 2019/8/30

Y1 - 2019/8/30

N2 - Introduction: Though seizures are a common complication after stroke, only little scientific evidence is available about the impact of epilepsy on cognitive functioning and quality of life in patients who have had a stroke. Therefore, we assessed these items in a case–control study. Methods: We studied 36 patients with poststroke epilepsy (PSE) and 36 matched patients who have had a stroke without epilepsy using parts of the FePsy (the computerized visual searching task (CVST) for central information processing speed and a reaction time test), the mini-mental-state examination (MMSE), the EuroQol, the stroke-adapted Sickness Impact Profile questionnaire (SA-SIP-30), the Barthel index, the modified Rankin scale, and the National Institutes of Health stroke scale (NIHSS). Results: Patients with PSE had significantly lower scores on the CVST and MMSE. Generic quality of life was the same in patients with poststroke epilepsy and patients with stroke only, however, the SA-SIP-30 showed a lower disease-specific quality of life in patients with poststroke epilepsy. The Barthel index showed no difference between both groups, but both the modified Rankin scale and the NIHSS were significantly higher in patients with poststroke epilepsy, indicating more disability and neurological impairment in patients with PSE. Conclusions: We found that PSE relates to impaired cognitive functioning, a lower disease-specific quality of life and more disability and neurological impairment. This underlines the importance of further clinical research in this field. This article is part of the Special Issue “Seizures & Stroke”

AB - Introduction: Though seizures are a common complication after stroke, only little scientific evidence is available about the impact of epilepsy on cognitive functioning and quality of life in patients who have had a stroke. Therefore, we assessed these items in a case–control study. Methods: We studied 36 patients with poststroke epilepsy (PSE) and 36 matched patients who have had a stroke without epilepsy using parts of the FePsy (the computerized visual searching task (CVST) for central information processing speed and a reaction time test), the mini-mental-state examination (MMSE), the EuroQol, the stroke-adapted Sickness Impact Profile questionnaire (SA-SIP-30), the Barthel index, the modified Rankin scale, and the National Institutes of Health stroke scale (NIHSS). Results: Patients with PSE had significantly lower scores on the CVST and MMSE. Generic quality of life was the same in patients with poststroke epilepsy and patients with stroke only, however, the SA-SIP-30 showed a lower disease-specific quality of life in patients with poststroke epilepsy. The Barthel index showed no difference between both groups, but both the modified Rankin scale and the NIHSS were significantly higher in patients with poststroke epilepsy, indicating more disability and neurological impairment in patients with PSE. Conclusions: We found that PSE relates to impaired cognitive functioning, a lower disease-specific quality of life and more disability and neurological impairment. This underlines the importance of further clinical research in this field. This article is part of the Special Issue “Seizures & Stroke”

KW - Cognitive function

KW - Poststroke epilepsy

KW - Quality of life

KW - Seizure

KW - Stroke

UR - http://www.scopus.com/inward/record.url?scp=85071443077&partnerID=8YFLogxK

U2 - 10.1016/j.yebeh.2019.106444

DO - 10.1016/j.yebeh.2019.106444

M3 - Article

JO - Epilepsy and Behavior

JF - Epilepsy and Behavior

SN - 1525-5050

M1 - 106444

ER -

van Tuijl JH, van Raak EPM, van Oostenbrugge RJ, Aldenkamp AP, Rouhl RPW. Cognition and quality of life in patients with poststroke epilepsy: a case–control study. Epilepsy and Behavior. 2019 Aug 30. 106444. Available from, DOI: 10.1016/j.yebeh.2019.106444