Abstract
The synthesis and characterization of both enantiomers of 2-(benzyloxy)-1-[3,5-bis[[3,5-bis(benzyloxy)]benzyloxy]benzyloxy]-3-[[3,5-bis(benzyloxy)]benzyloxy]propane (I; S-7 and R-7) are described. The chirality is based on the linkage of three constitutionally different, but chem. similar, dendritic wedges with a chiral glycerol derived core. Both enantiomers are synthesized from the same starting material: S-(+)-Solketal. Despite their enantiomeric purity, S-7 and R-7 lack any optical activity and may be regarded as the first macromol. analogs of the well-known org. mols. with \"accidental degeneracy\" or \"cryptochirality.\"
Original language | English |
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Pages (from-to) | 46-52 |
Number of pages | 7 |
Journal | Chirality |
Volume | 10 |
DOIs | |
Publication status | Published - 1998 |