Chemical composition and topology of poly(lactide-co-glycolide) revealed by pushing MALDI-TOF MS to its limit

S. Huijser, B.B.P. Staal, Juan Huang, R. Duchateau, C.E. Koning

Research output: Contribution to journalArticleAcademicpeer-review

37 Citations (Scopus)

Abstract

Software developed in house in combination with a recently developed method of MALDI-TOF MS enable not only the elucidation of individual chain structures of poly(lactide-co-glycolide), a polymer used extensively in the medical sector, but a full characterization of this copolymer including even its chemical composition and topology (random, gradient, block (see figure), or alternating).
Original languageEnglish
Pages (from-to)4104-4108
Number of pages5
JournalAngewandte Chemie - International Edition
Volume45
Issue number25
DOIs
Publication statusPublished - 2006

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