Cascade reactions in nanoreactors

M.C.M. van Oers, F.P.J.T. Rutjes, J.C.M. van Hest

Research output: Contribution to journalReview articleAcademicpeer-review

50 Citations (Scopus)


In an attempt to mimic the biosynthetic efficiencies of nature and in a search for greener, more sustainable alternatives to nowadays ways of producing chemicals, one-pot cascade reactions have attracted a lot of attention in the past decade. Since most catalysts are not compatible with each other, compartmentalization techniques have often been applied to prevent catalyst inactivation. A various array of nanoreactors have been developed to meet the demand of having a site-isolated catalyst system, while maintaining the catalyst activity. Both multienzyme nanoreactors as well as enzyme/metal catalyst or organocatalyst systems have shown great potential in one-pot cascade reactions and hold promise for future developments in this field.

Original languageEnglish
Pages (from-to)10-16
Number of pages7
JournalCurrent Opinion in Biotechnology
Publication statusPublished - Aug 2014
Externally publishedYes


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