Biological activity of Ha-based biomaterial mixes in a critical sized rabbit model

J.J.C. Arts, L.H.B. Walschot, N. Verdonschot, B.W. Schreurs, P. Buma

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review


The biological activity of different volume mixes of boneSafe with MCB in a critical sized rabbit model was discussed. Bilateral distal femoral defects were created in 20 female New Zealand White rabbits and filled with different bone graft materials. It was found that the empty defect was indeed critical sized. New bone formation was only found at the margins of the defect. It was also observed that the mixes of of BS and MCB are usable as bone graft extenders, but the final evaluation should be done in a clinical realistic and loaded model.

Original languageEnglish
Title of host publicationTransactions - 7th World Biomaterials Congress
Number of pages1
Publication statusPublished - 1 Dec 2004
Externally publishedYes
EventTransactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: 17 May 200421 May 2004

Publication series

NameTransactions - 7th World Biomaterials Congress


ConferenceTransactions - 7th World Biomaterials Congress


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