We have reported the self-assembly of nucleotide-attached bolaamphiphiles in aqueous solutions1). On the other hand, π -conjugated oligomers are one of the attentions in electro-optical chemistry2). In this research, we have synthesized an oligo(p-phenylenevinylene) having a thymidylic acid at each end, and examined its self-assembly and binary self-assembly with complementary oligoadenylic acid (dA20). The self-assembled structures were examined by AFM, FE-SEM, UV and CD spectroscopy. We can find non-helical columnar structures by AFM and FE-SEM observations from the self-assembly of T-OPV-T with diameters of 3.8 nm, which well fits with the molecular length of T-OPV-T. Helical columnar structures are observed from the binary self-assembly of T-OPV-T and dA20, with 5.8nm diameters and 35nm helical pitches. The UV and CD measurements reveal that the formation of complementary A-T base pairs and π- π stacking interaction between the OPV moieties in the binary-self-assembly.
|Number of pages||2|
|Publication status||Published - 1 Dec 2005|
|Event||54th SPSJ Symposium on Macromolecules - Yamagata, Japan|
Duration: 20 Sep 2005 → 22 Sep 2005
|Conference||54th SPSJ Symposium on Macromolecules|
|Period||20/09/05 → 22/09/05|
- Thymidylic Acid