TY - JOUR
T1 - Basics of Coronary Thermodilution
AU - Candreva, Alessandro
AU - Gallinoro, Emanuele
AU - van ’t Veer, Marcel
AU - Sonck, Jeroen
AU - Collet, Carlos
AU - Di Gioia, Giuseppe
AU - Kodeboina, Monika
AU - Mizukami, Takuya
AU - Nagumo, Sakura
AU - Keulards, Daniëlle
AU - Fournier, Stephane
AU - Pijls, Nico H.J.
AU - De Bruyne, Bernard
PY - 2021/3/22
Y1 - 2021/3/22
N2 - Coronary microvascular dysfunction is a highly prevalent condition in both obstructive and nonobstructive coronary artery disease. Intracoronary thermodilution is a promising technique to investigate coronary microvascular (dys)function in vivo and to assess its most important metric: microvascular resistance. Here, the authors provide a practical review of bolus and continuous thermodilution for the measurement of coronary flow and microvascular resistance. The authors describe the basic principles of indicator-dilution theory and of coronary thermodilution and detail the practicalities of their application in the catheterization laboratory. Finally, the authors discuss contemporary clinical applications of coronary thermodilution–based microvascular assessment in humans and future perspectives.
AB - Coronary microvascular dysfunction is a highly prevalent condition in both obstructive and nonobstructive coronary artery disease. Intracoronary thermodilution is a promising technique to investigate coronary microvascular (dys)function in vivo and to assess its most important metric: microvascular resistance. Here, the authors provide a practical review of bolus and continuous thermodilution for the measurement of coronary flow and microvascular resistance. The authors describe the basic principles of indicator-dilution theory and of coronary thermodilution and detail the practicalities of their application in the catheterization laboratory. Finally, the authors discuss contemporary clinical applications of coronary thermodilution–based microvascular assessment in humans and future perspectives.
KW - bolus coronary thermodilution
KW - continuous coronary thermodilution
KW - coronary microvascular dysfunction
KW - indicator-dilution theory
UR - http://www.scopus.com/inward/record.url?scp=85102125898&partnerID=8YFLogxK
U2 - 10.1016/j.jcin.2020.12.037
DO - 10.1016/j.jcin.2020.12.037
M3 - Review article
C2 - 33736767
AN - SCOPUS:85102125898
SN - 1936-8798
VL - 14
SP - 595
EP - 605
JO - JACC: Cardiovascular Interventions
JF - JACC: Cardiovascular Interventions
IS - 6
ER -