Atherosclerotic carotid bifurcation phantoms with stenotic soft inclusions for ultrasound flow and vessel wall elastography imaging

Boris Chayer, Marcel van den Hoven, Marie Hélene Roy Cardinal, Hongliang Li, Abigail Swillens, Richard Lopata, Guy Cloutier (Corresponding author)

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

Abstract

As the complexity of ultrasound signal processing algorithms increases, it becomes more difficult to demonstrate their added value and thus robust validation strategies are required. We propose a method of manufacturing ultrasonic vascular phantoms mimicking an atheromatous plaque in an internal carotid artery bifurcation for applications in flow imaging and elastography. During the fabrication process, a soft inclusion mimicking a stenotic lipid pool was embedded within the vascular wall. Mechanical testing measured Young's moduli of the vascular wall and soft inclusion at 342 ± 25 kPa and 17 ± 3 kPa, respectively. B-mode, color Doppler, power Doppler, shear wave elastography, and strain elastography images of the different phantoms were produced to show the validity of the fabrication process. Because of their realistic geometries and mechanical properties, those phantoms may become advantageous for fluid-structure experimental modeling and validation of new ultrasound-based imaging technologies.

Original languageEnglish
Article number095025
Number of pages12
JournalPhysics in Medicine and Biology
Volume64
Issue number9
DOIs
Publication statusPublished - 2 May 2019

Keywords

  • carotid atherosclerotic plaque
  • duplex ultrasound
  • flow loop experiments
  • phantom fabrication process
  • shear wave elastography
  • strain elastography
  • vascular phantom

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