Aqueous reductive amination using a dendritic metal catalyst in a dialysis bag

J.S. Willemsen, J.C.M. Hest, van, F.P.J.T. Rutjes

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)
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Abstract

Water-soluble dendritic iridium catalysts were synthesized by attaching a reactive metal complex to DAB-Am dendrimers via an adapted asymmetric bipyridine ligand. These dendritic catalysts were applied in the aqueous reductive amination of valine while contained in a dialysis bag. Comparable conversions were observed as for the noncompartmentalized counterparts, albeit with somewhat longer reaction times. These results clearly show that the encapsulated catalyst system is suitable to successfully drive a complex reaction mixture with various equilibrium reactions to completion.

Original languageEnglish
Pages (from-to)960-965
Number of pages6
JournalBeilstein Journal of Organic Chemistry
Volume9
DOIs
Publication statusPublished - 17 May 2013
Externally publishedYes

Bibliographical note

This article is part of the Thematic Series "Creating complexity".

Keywords

  • Aqueous reductive amination
  • Cascade catalysis
  • Compartmentalization
  • Dendritic catalysts
  • Dialysis

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