The separation and analysis of low concentrations of organic compounds in complex sample matrices, such as petroleum products, waste and drinking water, food, beverages and pharmaceutical products is a rather complex analytical problem. Current methods are hampered by insufficient resolution obtained by single capillary columns even if they have rather high plate numbers. In this paper the potential of a combination of programmed temperature sample introduction and mass flow controlled multi column dual oven capillary gas chromatography and on-line mass spectrometry will be discussed and illustrated. The effect of cold trapping in between the columns for components with a moderate volatility will be demonstrated for different applications dealing with the determination of trace impurities in various main products such as gasoline, aromatics, steroids and anilin.
|Title of host publication||Proceedings of the 14th International Symposium on Capillary Chromatography, 25-29 May,1992, Baltimore, USA|
|Editors||P. Sandra, M.L. Lee|
|Place of Publication||Heidelberg|
|Publication status||Published - 1992|
|Event||14th International Symposium on Capillary Chromatography - Stouffer Harborplace Hotel, Baltimore, United States|
Duration: 25 May 1992 → 29 May 1992
|Conference||14th International Symposium on Capillary Chromatography|
|Period||25/05/92 → 29/05/92|
Hoffman, A., Staniewski, J., Bremer, R., Rogies, F., & Rijks, J. A. (1992). Applications of mass flow controlled multicolumn switching in on-line capillary GC-MS. In P. Sandra, & M. L. Lee (Eds.), Proceedings of the 14th International Symposium on Capillary Chromatography, 25-29 May,1992, Baltimore, USA (pp. 624-631). Heidelberg: Huethig.