Abstract
No wash, just go: Classical antibody-detection methods rely on heterogeneous detection schemes that involve multiple, time-consuming binding and washing steps. Here we present a new concept to translate the antigen–antibody interaction directly into a readily detectable fluorescent signal by using a single-chain sensor protein and taking advantage of the unique Y-shaped structure common to all antibodies
Original language | English |
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Pages (from-to) | 2264-2267 |
Journal | ChemBioChem |
Volume | 11 |
Issue number | 16 |
DOIs | |
Publication status | Published - 2011 |