TY - JOUR
T1 - Anomalous behaviour of sodium in isotachophoresis
AU - Reijenga, J.C.
AU - Verheggen, T.P.E.M.
PY - 1991
Y1 - 1991
N2 - Using a cationic operational system in capillary isotachophoresis, millimolar concentrations of sodium were determined in the absence and presence of serum proteins. With several internal standards, the reproducibility of the sodium determination was significantly poorer in the presence of proteins, even after partial thermal degradation. The results are explained by protein—sodium interaction in the injection port, where the electric field strength was sixteen times lower than in the separation capillary.
AB - Using a cationic operational system in capillary isotachophoresis, millimolar concentrations of sodium were determined in the absence and presence of serum proteins. With several internal standards, the reproducibility of the sodium determination was significantly poorer in the presence of proteins, even after partial thermal degradation. The results are explained by protein—sodium interaction in the injection port, where the electric field strength was sixteen times lower than in the separation capillary.
U2 - 10.1016/S0021-9673(01)88741-0
DO - 10.1016/S0021-9673(01)88741-0
M3 - Article
SN - 0021-9673
VL - 545
SP - 471
EP - 474
JO - Journal of Chromatography
JF - Journal of Chromatography
IS - 2
ER -