Anatomically Realistic Neonatal Heart Model for Use in Neonatal Patient Simulators

M.W.H. Thielen (Corresponding author), F.L.M. Delbressine, S. Bambang Oetomo, L.M.G. Feijs

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)
174 Downloads (Pure)


Neonatal patient simulators (NPS) are artificial patient surrogates used in the context of medical simulation training. Neonatologists and nursing staff practice clinical interventions such as chest compressions to ensure patient survival in the case of bradycardia or cardiac arrest. The simulators used currently are of low physical fidelity and therefore cannot provide qualitative insight into the procedure of chest compressions. The embedding of an anatomically realistic heart model in future simulators enables the detection of cardiac output generated during chest compressions; this can provide clinicians with an output parameter, which can deepen the understanding of the effect of the compressions in relation to the amount of blood flow generated. Before this monitoring can be achieved, an anatomically realistic heart model must be created containing: two atria, two ventricles, four heart valves, pulmonary veins and arteries, and systemic veins and arteries. This protocol describes the procedure for creating such a functional artificial neonatal heart model by utilizing a combination of magnetic resonance imaging (MRI), 3D printing, and casting in the form of cold injection molding. Using this method with flexible 3D printed inner molds in the injection molding process, an anatomically realistic heart model can be obtained.

Original languageEnglish
Article numbere56710
Number of pages11
JournalJournal of Visualized Experiments (JoVE)
Issue number144
Publication statusPublished - 5 Feb 2019


  • newborn
  • heart
  • replica
  • 3D printing
  • Bioengineering
  • artificial organs
  • medicaltraining
  • Neonatology
  • Molds
  • manikin
  • Issue 144
  • heart model
  • medicalsimulation


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