An MR-compatible bicycle ergometer for in-magnet whole-body human exercise testing

J.A.L. Jeneson, J.P.J. Schmitz, P.A.J. Hilbers, K. Nicolaij

Research output: Contribution to journalArticleAcademicpeer-review

32 Citations (Scopus)


An MR-compatible ergometer was developed for in-magnet whole-body human exercise testing. Designed on the basis of conventional mechanically braked bicycle ergometers and constructed from nonferrous materials, the ergometer was implemented on a 1.5-T whole-body MR scanner. A spectrometer interface was constructed using standard scanner hardware, complemented with custom-built parts and software to enable gated data acquisition during exercise. High-quality 31P NMR spectra were reproducibly obtained from the medial head of the quadriceps muscle of the right leg of eight healthy subjects during two-legged high-frequency pedaling (80 revolutions per minute) at three incremental workloads, including maximal. Muscle phosphocreatine content dropped 82%, from 32.2 ± 1.0 mM at rest to 5.7 ± 1.1 mM at maximal workload (mean ± standard error; n = 8), indicating that the majority of quadriceps motor units were recruited. The cardiovascular load of the exercise was likewise significant, as evidenced by heart rates of 150 (±10%) beats per minute, measured immediately afterward. As such, the newly developed MR bicycling exercise equipment offers a powerful new tool for clinical musculoskeletal and cardiovascular MR investigation. The basic design of the ergometer is highly generic and adaptable for application on a wide selection of whole-body MR scanners.
Original languageEnglish
Pages (from-to)257-261
JournalMagnetic Resonance in Medicine
Issue number1
Publication statusPublished - 2010


Dive into the research topics of 'An MR-compatible bicycle ergometer for in-magnet whole-body human exercise testing'. Together they form a unique fingerprint.

Cite this