A patient-specific model describing the primary relations between the cardiac muscle contraction and coronary circulation might be useful for interpreting coronary hemodynamics and deciding on medical treatment in case multiple types of coronary circulatory disease are present. For this purpose we present the use of a microstructure-based heart contraction model and a micro-structure based fiber reinforced arterial wall model as the basis of a 1D wave propagation model to describe coronary pressure and flow waves. We conclude that this extended pulse wave propagation model adequately can predict coronary hemodynamics in both normal and diseased state based on patient-specific clinical data.
|Title of host publication||3rd International Conference on Computational and Mathematical Biomedical Engineering,|
|Editors||P. Nithiarasu, R. Löhner|
|Publication status||Published - 2013|
|Event||3rd International Conference on Computational & Mathematical Biomedical Engineering (CMBE13) - City University of Hong Kong, Hong Kong, China|
Duration: 16 Dec 2013 → 18 Dec 2013
|Conference||3rd International Conference on Computational & Mathematical Biomedical Engineering (CMBE13)|
|Period||16/12/13 → 18/12/13|