TY - JOUR
T1 - Amplification of chirality in helical supramolecular columns
AU - Brunsveld, L.
AU - Lohmeijer, B.G.G.
AU - Vekemans, J.A.J.M.
AU - Meijer, E.W.
PY - 2001
Y1 - 2001
N2 - Strong amplification of chirality occurs in dynamic, but highly ordered, helical columns in n-butanol. for which one chiral seed molecule suffices to render a column of 400 molecules to become homochiral. The chiral columns are formed in a thermally dependent stepwise process. The transition from achiral stacks to helical columns is highly cooperative owing to well-defined intermolecular interactions. 'Sergeant and Soldiers' measurements allow for the calculation of the association constant and cooperativity length of the homochiral segments. The 'Sergeant and Soldiers' data on the number of molecules within a column show a strikingly good match with data obtained from a theoretical model describing the self-assembly of the discotic molecules as a function of temperature and concentration
AB - Strong amplification of chirality occurs in dynamic, but highly ordered, helical columns in n-butanol. for which one chiral seed molecule suffices to render a column of 400 molecules to become homochiral. The chiral columns are formed in a thermally dependent stepwise process. The transition from achiral stacks to helical columns is highly cooperative owing to well-defined intermolecular interactions. 'Sergeant and Soldiers' measurements allow for the calculation of the association constant and cooperativity length of the homochiral segments. The 'Sergeant and Soldiers' data on the number of molecules within a column show a strikingly good match with data obtained from a theoretical model describing the self-assembly of the discotic molecules as a function of temperature and concentration
U2 - 10.1023/A:1014417621324
DO - 10.1023/A:1014417621324
M3 - Article
SN - 1388-3127
VL - 41
SP - 61
EP - 64
JO - Journal of Inclusion Phenomena and Macrocyclic Chemistry
JF - Journal of Inclusion Phenomena and Macrocyclic Chemistry
IS - 1-4
ER -