Adaptive reorientation of cardiac myofibers: Comparison of left ventricular shear in model and experiment

J.W. Kroon, T. Delhaas, P.H.M. Bovendeerd, M.G.J. Arts

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

4 Citations (Scopus)

Abstract

Mechanical load plays an important role in cardiac growth and remodeling. In a previous mathematical model study the hypothesis was tested that fiber cross-fiber shear acts as a stimulus for remodeling of the pattern of myofiber orientations [7]. It was found that reorientation in response to fiber cross-fiber shear yielded realistic longitudinal and transmural components of myofiber orientation. In this study, we investigated whether circumferential-radial shear, as determined experimentally with magnetic resonance tagging, can be reproduced in the model as well. Our results show that after myofiber reorientation differences in circumferential-radial shear between model and experiment were reduced significantly. However, a complete match could not be obtained through shear-induced myofiber reorientation alone.
Original languageEnglish
Title of host publicationFunctional Imaging and Modeling of the Heart : proceedings of the 5th Intrenational conference (FIMH 2009), June 3-5, 2009, Nice France
EditorsN. Ayache, H. Delingette, M. Sermesant
Place of PublicationBerlin
PublisherSpringer
Pages58-67
ISBN (Print)978-3-642-01931-9
DOIs
Publication statusPublished - 2009

Publication series

NameLecture Notes in Computer Science
Volume5528
ISSN (Print)0302-9743

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