Active tracked intramyocardial catheter injections for regenerative therapy with real-time MR guidance: Feasibility in the porcine heart

Cheyenne C.S. Tseng; Steven Wenker; Maarten H. Bakker; Adriaan O. Kraaijeveld; Patricia Y.W. Dankers; Peter R. Seevinck; Jouke Smink; Scott Kimmel; Frebus J. van Slochteren; Steven A.J. Chamuleau

doi:10.4244/EIJ-D-17-01081

Active tracked intramyocardial catheter injections for regenerative therapy with real-time MR guidance: Feasibility in the porcine heart

Cheyenne C.S. Tseng, Steven Wenker, Maarten H. Bakker, Adriaan O. Kraaijeveld, Patricia Y.W. Dankers, Peter R. Seevinck, Jouke Smink, Scott Kimmel, Frebus J. van Slochteren, Steven A.J. Chamuleau

Biomedical Materials and Chemistry

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

The MIGRATE (MrI Guided RegenerAtive ThErapy) consortium is a combined scientific and industrial effort to establish an MRIguided intramyocardial injection platform. By collaborating within the MIGRATE consortium we were able to combine state-of-theart interventional imaging hardware, software, MRI-compatible catheters, and biomaterials. In this pilot study, we demonstrated the feasibility of intramyocardial injections of an MRI-visible biomaterial by interventional MRI using a combination of active tracking and passive visualisation.

Original language	English
Pages (from-to)	E336-E339
Number of pages	4
Journal	EuroIntervention
Volume	15
Issue number	4
DOIs	https://doi.org/10.4244/EIJ-D-17-01081
Publication status	Published - Jul 2019

Bibliographical note

Funding Information:
This work was performed at the UMC Utrecht with support from partners of the MIGRATE consortium: Philips Research, University of Technology Eindhoven, CART-Tech, Imricor Medical Systems, Nano4Imaging, Cook Medical, Personal Space Technologies, Netherlands Heart Institute and the Dutch Heart Foundation.

Funding Information:
This work was conducted with financial support from the NHS, ICIN-Netherlands Heart Foundation and partners of the MIGRATE consortium (within the TKI LSH framework).

Publisher Copyright:
© 2019 Pensoft Publishers. All rights reserved.

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Tseng, C. C. S., Wenker, S., Bakker, M. H., Kraaijeveld, A. O., Dankers, P. Y. W., Seevinck, P. R., Smink, J., Kimmel, S., van Slochteren, F. J., & Chamuleau, S. A. J. (2019). Active tracked intramyocardial catheter injections for regenerative therapy with real-time MR guidance: Feasibility in the porcine heart. EuroIntervention, 15(4), E336-E339. https://doi.org/10.4244/EIJ-D-17-01081

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title = "Active tracked intramyocardial catheter injections for regenerative therapy with real-time MR guidance: Feasibility in the porcine heart",

abstract = "The MIGRATE (MrI Guided RegenerAtive ThErapy) consortium is a combined scientific and industrial effort to establish an MRIguided intramyocardial injection platform. By collaborating within the MIGRATE consortium we were able to combine state-of-theart interventional imaging hardware, software, MRI-compatible catheters, and biomaterials. In this pilot study, we demonstrated the feasibility of intramyocardial injections of an MRI-visible biomaterial by interventional MRI using a combination of active tracking and passive visualisation.",

author = "Tseng, {Cheyenne C.S.} and Steven Wenker and Bakker, {Maarten H.} and Kraaijeveld, {Adriaan O.} and Dankers, {Patricia Y.W.} and Seevinck, {Peter R.} and Jouke Smink and Scott Kimmel and {van Slochteren}, {Frebus J.} and Chamuleau, {Steven A.J.}",

note = "Funding Information: This work was performed at the UMC Utrecht with support from partners of the MIGRATE consortium: Philips Research, University of Technology Eindhoven, CART-Tech, Imricor Medical Systems, Nano4Imaging, Cook Medical, Personal Space Technologies, Netherlands Heart Institute and the Dutch Heart Foundation. Funding Information: This work was conducted with financial support from the NHS, ICIN-Netherlands Heart Foundation and partners of the MIGRATE consortium (within the TKI LSH framework). Publisher Copyright: {\textcopyright} 2019 Pensoft Publishers. All rights reserved.",

year = "2019",

month = jul,

doi = "10.4244/EIJ-D-17-01081",

language = "English",

volume = "15",

pages = "E336--E339",

journal = "EuroIntervention",

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Tseng, CCS, Wenker, S, Bakker, MH, Kraaijeveld, AO, Dankers, PYW, Seevinck, PR, Smink, J, Kimmel, S, van Slochteren, FJ & Chamuleau, SAJ 2019, 'Active tracked intramyocardial catheter injections for regenerative therapy with real-time MR guidance: Feasibility in the porcine heart', EuroIntervention, vol. 15, no. 4, pp. E336-E339. https://doi.org/10.4244/EIJ-D-17-01081

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T1 - Active tracked intramyocardial catheter injections for regenerative therapy with real-time MR guidance

T2 - Feasibility in the porcine heart

AU - Tseng, Cheyenne C.S.

AU - Wenker, Steven

AU - Bakker, Maarten H.

AU - Kraaijeveld, Adriaan O.

AU - Dankers, Patricia Y.W.

AU - Seevinck, Peter R.

AU - Smink, Jouke

AU - Kimmel, Scott

AU - van Slochteren, Frebus J.

AU - Chamuleau, Steven A.J.

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PY - 2019/7

Y1 - 2019/7

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AB - The MIGRATE (MrI Guided RegenerAtive ThErapy) consortium is a combined scientific and industrial effort to establish an MRIguided intramyocardial injection platform. By collaborating within the MIGRATE consortium we were able to combine state-of-theart interventional imaging hardware, software, MRI-compatible catheters, and biomaterials. In this pilot study, we demonstrated the feasibility of intramyocardial injections of an MRI-visible biomaterial by interventional MRI using a combination of active tracking and passive visualisation.

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Active tracked intramyocardial catheter injections for regenerative therapy with real-time MR guidance: Feasibility in the porcine heart

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