A system for on-line monitoring of light element concentration distributions in thin samples

P.J.M. Brands, P.H.A. Mutsaers, M.J.A. Voigt, de

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    6 Citations (Scopus)


    At the Cyclotron Laboratory, a scanning proton microprobe is used to determine concentration distributions in biomedical samples. The data acquired in these measurements used to be analysed in a time consuming off-line analysis. To avoid the loss of valuable measurement and analysis time, DYANA was developed. DYANA is an on-line method for the analysis of data from biomedical measurements. By using a database of background shapes, light elements such as Na and Mg, can be fitted even more precisely than in conventional fitting procedures. The entire analysis takes only several seconds and is performed while the acquisition system is gathering a new subset of data. Data acquisition must be guaranteed and may not be interfered by other parallel processes. Therefore, the analysis, the data acquisition and the experiment control is performed on a PCI-based Pentium personal computer (PC), running a real-time operating system. A second PC is added to run a graphical user interface for interaction with the experimenter and the monitoring of the analysed results. The system is here illustrated using atherosclerotic tissue but is applicable to all kinds of thin samples.
    Original languageEnglish
    Pages (from-to)135-140
    Number of pages6
    JournalNuclear Instruments and Methods in Physics Research. Section B: Beam Interactions with Materials and Atoms
    Issue number1-4
    Publication statusPublished - 1999


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