A supramolecular system for the electrochemically controlled release of cells

Qi An; Jenny Brinkmann; Jurriaan Huskens; Sven Krabbenborg; Jan de Boer; Pascal Jonkheijm

doi:10.1002/anie.201205651

A supramolecular system for the electrochemically controlled release of cells

Qi An, Jenny Brinkmann, Jurriaan Huskens, Sven Krabbenborg, Jan de Boer, Pascal Jonkheijm

Research output: Contribution to journal › Article › Academic › peer-review

113 Citations (Scopus)

Abstract

Please release me: Electrochemically activated cell release is achieved using a redox-active supramolecular complex (see picture). Host molecule CB[8] (green) links surface-bound viologen (purple) with solution-exposed RGD peptides (red). Electrochemical reduction dissociates the complex, releases the peptides, and thus releases the cells from the substrates. This supramolecular strategy is also applicable to microelectrodes.

Original language	English
Pages (from-to)	12233-12237
Number of pages	5
Journal	Angewandte Chemie - International Edition
Volume	51
Issue number	49
DOIs	https://doi.org/10.1002/anie.201205651
Publication status	Published - 3 Dec 2012
Externally published	Yes

Keywords

cell detachment
host-guest systems
stimuli responsive
supramolecular chemistry

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10.1002/anie.201205651

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AU - Jonkheijm, Pascal

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A supramolecular system for the electrochemically controlled release of cells

Abstract

Keywords

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