A simple and convenient synthesis of 2-methoxyestradiol from estrone

A. P. Prakasham; Karuna Shanker; Arvind S. Negi

doi:10.1016/j.steroids.2012.01.005

A simple and convenient synthesis of 2-methoxyestradiol from estrone

A. P. Prakasham, Karuna Shanker, Arvind S. Negi

Research output: Contribution to journal › Article › Academic › peer-review

7 Citations (Scopus)

Abstract

A simple and straightforward synthesis of 2-methoxyestradiol have been achieved in nine synthetic steps with 21% of overall yield. Being a convenient process, it can be upscaled to industrial process.

Original language	English
Pages (from-to)	467-470
Number of pages	4
Journal	Steroids
Volume	77
Issue number	5
DOIs	https://doi.org/10.1016/j.steroids.2012.01.005
Publication status	Published - Apr 2012
Externally published	Yes

Bibliographical note

Funding Information:
The authors are thankful to Director CSIR-CIMAP for constant help and support. This work was financially supported by CSIR . CSIR Research Internship to AP Prakasham is duly acknowledged.

Funding

The authors are thankful to Director CSIR-CIMAP for constant help and support. This work was financially supported by CSIR . CSIR Research Internship to AP Prakasham is duly acknowledged.

Keywords

2-Methoxyestradiol
Breast cancer
Total synthesis

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.steroids.2012.01.005

Cite this

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title = "A simple and convenient synthesis of 2-methoxyestradiol from estrone",

abstract = "A simple and straightforward synthesis of 2-methoxyestradiol have been achieved in nine synthetic steps with 21% of overall yield. Being a convenient process, it can be upscaled to industrial process.",

keywords = "2-Methoxyestradiol, Breast cancer, Total synthesis",

author = "Prakasham, {A. P.} and Karuna Shanker and Negi, {Arvind S.}",

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AU - Prakasham, A. P.

AU - Shanker, Karuna

AU - Negi, Arvind S.

N1 - Funding Information: The authors are thankful to Director CSIR-CIMAP for constant help and support. This work was financially supported by CSIR . CSIR Research Internship to AP Prakasham is duly acknowledged.

PY - 2012/4

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N2 - A simple and straightforward synthesis of 2-methoxyestradiol have been achieved in nine synthetic steps with 21% of overall yield. Being a convenient process, it can be upscaled to industrial process.

AB - A simple and straightforward synthesis of 2-methoxyestradiol have been achieved in nine synthetic steps with 21% of overall yield. Being a convenient process, it can be upscaled to industrial process.

KW - 2-Methoxyestradiol

KW - Breast cancer

KW - Total synthesis

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JO - Steroids

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A simple and convenient synthesis of 2-methoxyestradiol from estrone

Abstract

Bibliographical note

Funding

Keywords

UN SDGs

Access to Document

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