A multiscale model of the electrohysterogram the BioModUE-PTL project

Catherine Marque, Jeremy Laforet, Chiara Rabotti, Asgeir Alexandersson, Guy Germain, Jean Gondry, Brynjar Karlsson, Brane Leskosek, Massimo Mischi, Charles Muszinski, Guid Oei, Jan Peuscher, Drago Rudel

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

5 Citations (Scopus)

Abstract

The electrohysterogram (EHG) is a promising means of monitoring pregnancy and of detecting a risk of preterm labor. To improve our understanding of the EHG as well as its relationship with the physiologic phenomena involved in uterine contractility, we plan to model these phenomena in terms of generation and propagation of uterine electrical activity. This activity can be realistically modeled by representing the principal ionic dynamics at the cell level, the propagation of electrical activity at the tissue level and then the way it is reflected on the skin surface through the intervening tissue. We present in this paper the different steps leading to the development and validation of a biophysics based multiscale model of the EHG, going from the cell to the electrical signal measured on the abdomen.

Original languageEnglish
Title of host publication2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013
Place of PublicationPiscataway
PublisherInstitute of Electrical and Electronics Engineers
Pages7448-7451
Number of pages4
ISBN (Print)978-1-4577-0216-7
DOIs
Publication statusPublished - 31 Oct 2013
Event2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013 - Osaka, Japan
Duration: 3 Jul 20137 Jul 2013

Conference

Conference2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013
CountryJapan
CityOsaka
Period3/07/137/07/13

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    Marque, C., Laforet, J., Rabotti, C., Alexandersson, A., Germain, G., Gondry, J., Karlsson, B., Leskosek, B., Mischi, M., Muszinski, C., Oei, G., Peuscher, J., & Rudel, D. (2013). A multiscale model of the electrohysterogram the BioModUE-PTL project. In 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013 (pp. 7448-7451). [6611280] Institute of Electrical and Electronics Engineers. https://doi.org/10.1109/EMBC.2013.6611280