A model for educational simulation of hemodynamic transitions at birth

Carla D. Sá-Couto, Peter Andriessen, Willem L. Van Meurs, Diogo Ayres-de-Campos, Pedro M. Sá-Couto

Research output: Contribution to journalArticleAcademicpeer-review

14 Citations (Scopus)


Birth is characterized by swift and complex transitions in hemodynamic and respiratory variables. Unrecognized pathologies or incidents may quickly become fatal or cause permanent damage. This article introduces an essential component of an acute perinatal care simulator, namely a model for educational simulation of normal hemodynamic transitions seen during and shortly after birth. We explicitly formulate educational objectives and adapt a preexisting model for the simulation of neonatal cardiovascular physiology to include essential aspects of fetal hemodynamics. From the scientific literature, we obtain model parameters that characterize these aspects quantitatively. The fetal model is controlled by a time- and event-based script of changes occurring at birth, such as onset of breathing and cord clamping, and the transitory phase up to 24 h after birth. Comparison of simulation results with published target data confirms that realistic simulated hemodynamic vital signs are achieved.

Original languageEnglish
Pages (from-to)158-165
Number of pages8
JournalPediatric Research
Issue number2
Publication statusPublished - Feb 2010
Externally publishedYes


  • Blood Flow Velocity
  • Blood Pressure
  • Computer Simulation
  • Constriction
  • Fetus/blood supply
  • Hemodynamics
  • Humans
  • Infant, Newborn
  • Models, Cardiovascular
  • Parturition
  • Perinatal Care
  • Regional Blood Flow
  • Reproducibility of Results
  • Respiration, Artificial
  • Respiratory Mechanics
  • Time Factors
  • Umbilical Cord/blood supply


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