A model based simulation toolkit for evaluating renal replacement policies

B. Celik, P.M.E. Van Gorp, A.C.J. Snoeck, R.C. van Riet, P.J. de Winter, A. Wilbik

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

1 Citation (Scopus)
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Renal failure concerns progressive loss of kidney function. Renal Replacement Therapy (RRT) is a costly, long-running process that includes several decision points in different stages. Small changes in the protocol can impact significantly the expenditures and healthcare outcomes. Unfortunately, policy makers have very little support for benchmarking improvement alternatives. The existing models are designed to fit certain applications with preset parameters and design choices which do not match with the requirements of a policy analysis. A generic approach is required to analyze the effects of different design options adjustable to finer scales. To remedy this, this paper describes a novel toolkit for evaluating renal replacement policies, containing a parametrized colored Petri-Net which can be configured for the specifics of local settings. The model is made available for open access to overcome the non-replicability issue of existing models.

Original languageEnglish
Title of host publicationWSC'17 : 2017 Winter Simulation Conference : WSC turns 50: simulation everywhere! : December 3-6, 2017, Red Rock Casino Resort & Spa, Las Vegas
EditorsW.K. Chan, A. D’Ambrogio, G. Zacharewicz, N. Mustafee, G. Wainer, E.H. Page
PublisherInstitute of Electrical and Electronics Engineers
Number of pages12
VolumePart F134102
ISBN (Electronic)9781538634288
ISBN (Print)978-1-5386-3430-1
Publication statusPublished - 4 Jan 2018
Event2017 Winter Simulation Conference, WSC 2017 - Las Vegas, United States
Duration: 3 Dec 20176 Dec 2017


Conference2017 Winter Simulation Conference, WSC 2017
Abbreviated titleWSC 2017
Country/TerritoryUnited States
CityLas Vegas
Internet address


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