A micro-optofluidic sensor system based on PET sensing for real time sodium concentration measurement

M.K. Sharma, A.J.H. Frijns, J.P. Kooman, D.M.J. Smeulders

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We present a micro-optofluidic device with an integrated optical fiber to enable real time electrolyte measurements. The target application is, in-line electrolyte monitoring during dialysis. The device is fabricated in PDMS (polydimethylsiloxane) using soft-lithography. The optical sensing principle is based on selective fluorescence quenching of PET (photoinduced electron transfer) ON-OFF process. We have covalently immobilized these PET sensor molecules on the PDMS microchannel walls. A proof-of-concept device is presented for sodium concentrations measurement in a flowing medium. The first results show a clear relation between sodium concentrations and fluorescence intensity.
Original languageEnglish
Title of host publicationProceedings of the 5th European Conference on Microfluidics
EditorsJürgen Brandner, Stéphane Colin, David Newport, Christophe Serra
Place of PublicationParis
ISBN (Electronic)979-10-93567-17-4
Publication statusPublished - 28 Feb 2018
Event5th European Conference on Microfluidics (µFlu’18) - Strassbourg, France
Duration: 28 Feb 20182 Mar 2018
Conference number: 5


Conference5th European Conference on Microfluidics (µFlu’18)
Abbreviated titleµFlu’18
Internet address

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