A micro-optofluidic sensor system based on PET sensing for real time sodium concentration measurement

M.K. Sharma; A.J.H. Frijns; J.P. Kooman; D.M.J. Smeulders

A micro-optofluidic sensor system based on PET sensing for real time sodium concentration measurement

M.K. Sharma, A.J.H. Frijns, J.P. Kooman, D.M.J. Smeulders

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

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Abstract

We present a micro-optofluidic device with an integrated optical fiber to enable real time electrolyte measurements. The target application is, in-line electrolyte monitoring during dialysis. The device is fabricated in PDMS (polydimethylsiloxane) using soft-lithography. The optical sensing principle is based on selective fluorescence quenching of PET (photoinduced electron transfer) ON-OFF process. We have covalently immobilized these PET sensor molecules on the PDMS microchannel walls. A proof-of-concept device is presented for sodium concentrations measurement in a flowing medium. The first results show a clear relation between sodium concentrations and fluorescence intensity.

Original language	English
Title of host publication	Proceedings of the 5th European Conference on Microfluidics
Editors	Jürgen Brandner, Stéphane Colin, David Newport, Christophe Serra
Place of Publication	Paris
Publisher	SHF
Pages	89-92
ISBN (Electronic)	979-10-93567-17-4
Publication status	Published - 28 Feb 2018
Event	5th European Conference on Microfluidics (µFlu’18) - Strassbourg, France Duration: 28 Feb 2018 → 2 Mar 2018 Conference number: 5 http://mflu-negf-2018.com/

Conference

Conference	5th European Conference on Microfluidics (µFlu’18)
Abbreviated title	µFlu’18
Country/Territory	France
City	Strassbourg
Period	28/02/18 → 2/03/18
Internet address	http://mflu-negf-2018.com/

Cite this

@inproceedings{8eb0cee02f224260ace26bbe9e30c312,

title = "A micro-optofluidic sensor system based on PET sensing for real time sodium concentration measurement",

abstract = "We present a micro-optofluidic device with an integrated optical fiber to enable real time electrolyte measurements. The target application is, in-line electrolyte monitoring during dialysis. The device is fabricated in PDMS (polydimethylsiloxane) using soft-lithography. The optical sensing principle is based on selective fluorescence quenching of PET (photoinduced electron transfer) ON-OFF process. We have covalently immobilized these PET sensor molecules on the PDMS microchannel walls. A proof-of-concept device is presented for sodium concentrations measurement in a flowing medium. The first results show a clear relation between sodium concentrations and fluorescence intensity.",

author = "M.K. Sharma and A.J.H. Frijns and J.P. Kooman and D.M.J. Smeulders",

year = "2018",

month = feb,

day = "28",

language = "English",

pages = "89--92",

editor = "Brandner, {J{\"u}rgen } and St{\'e}phane Colin and David Newport and Christophe Serra",

booktitle = "Proceedings of the 5th European Conference on Microfluidics",

publisher = "SHF",

note = "5th European Conference on Microfluidics (µFlu{\textquoteright}18), µFlu{\textquoteright}18 ; Conference date: 28-02-2018 Through 02-03-2018",

url = "http://mflu-negf-2018.com/",

}

Sharma, MK, Frijns, AJH, Kooman, JP & Smeulders, DMJ 2018, A micro-optofluidic sensor system based on PET sensing for real time sodium concentration measurement. in J Brandner, S Colin, D Newport & C Serra (eds), Proceedings of the 5th European Conference on Microfluidics. SHF, Paris, pp. 89-92, 5th European Conference on Microfluidics (µFlu’18), Strassbourg, France, 28/02/18.

A micro-optofluidic sensor system based on PET sensing for real time sodium concentration measurement. / Sharma, M.K.; Frijns, A.J.H.; Kooman, J.P.; Smeulders, D.M.J.

Proceedings of the 5th European Conference on Microfluidics. ed. / Jürgen Brandner; Stéphane Colin; David Newport; Christophe Serra. Paris : SHF, 2018. p. 89-92.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

TY - GEN

T1 - A micro-optofluidic sensor system based on PET sensing for real time sodium concentration measurement

AU - Sharma, M.K.

AU - Frijns, A.J.H.

AU - Kooman, J.P.

AU - Smeulders, D.M.J.

N1 - Conference code: 5

PY - 2018/2/28

Y1 - 2018/2/28

N2 - We present a micro-optofluidic device with an integrated optical fiber to enable real time electrolyte measurements. The target application is, in-line electrolyte monitoring during dialysis. The device is fabricated in PDMS (polydimethylsiloxane) using soft-lithography. The optical sensing principle is based on selective fluorescence quenching of PET (photoinduced electron transfer) ON-OFF process. We have covalently immobilized these PET sensor molecules on the PDMS microchannel walls. A proof-of-concept device is presented for sodium concentrations measurement in a flowing medium. The first results show a clear relation between sodium concentrations and fluorescence intensity.

AB - We present a micro-optofluidic device with an integrated optical fiber to enable real time electrolyte measurements. The target application is, in-line electrolyte monitoring during dialysis. The device is fabricated in PDMS (polydimethylsiloxane) using soft-lithography. The optical sensing principle is based on selective fluorescence quenching of PET (photoinduced electron transfer) ON-OFF process. We have covalently immobilized these PET sensor molecules on the PDMS microchannel walls. A proof-of-concept device is presented for sodium concentrations measurement in a flowing medium. The first results show a clear relation between sodium concentrations and fluorescence intensity.

M3 - Conference contribution

SP - 89

EP - 92

BT - Proceedings of the 5th European Conference on Microfluidics

A2 - Brandner, Jürgen

A2 - Colin, Stéphane

A2 - Newport, David

A2 - Serra, Christophe

PB - SHF

CY - Paris

T2 - 5th European Conference on Microfluidics (µFlu’18)

Y2 - 28 February 2018 through 2 March 2018

ER -