A micro-optofluidic sensor system based on PET sensing for real time sodium concentration measurement

M.K. Sharma, A.J.H. Frijns, J.P. Kooman, D.M.J. Smeulders

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Abstract

We present a micro-optofluidic device with an integrated optical fiber to enable real time electrolyte measurements. The target application is, in-line electrolyte monitoring during dialysis. The device is fabricated in PDMS (polydimethylsiloxane) using soft-lithography. The optical sensing principle is based on selective fluorescence quenching of PET (photoinduced electron transfer) ON-OFF process. We have covalently immobilized these PET sensor molecules on the PDMS microchannel walls. A proof-of-concept device is presented for sodium concentrations measurement in a flowing medium. The first results show a clear relation between sodium concentrations and fluorescence intensity.
LanguageEnglish
Title of host publicationProceedings of the 5th European Conference on Microfluidics
EditorsJürgen Brandner, Stéphane Colin, David Newport, Christophe Serra
Place of PublicationParis
PublisherSHF
Pages89-92
ISBN (Electronic)979-10-93567-17-4
StatePublished - 28 Feb 2018
Event5th European Conference on Microfluidics (µFlu’18) - Strassbourg, France
Duration: 28 Feb 20182 Mar 2018
Conference number: 5
http://mflu-negf-2018.com/

Conference

Conference5th European Conference on Microfluidics (µFlu’18)
Abbreviated titleµFlu’18
CountryFrance
CityStrassbourg
Period28/02/182/03/18
Internet address

Cite this

Sharma, M. K., Frijns, A. J. H., Kooman, J. P., & Smeulders, D. M. J. (2018). A micro-optofluidic sensor system based on PET sensing for real time sodium concentration measurement. In J. Brandner, S. Colin, D. Newport, & C. Serra (Eds.), Proceedings of the 5th European Conference on Microfluidics (pp. 89-92). Paris: SHF.
Sharma, M.K. ; Frijns, A.J.H. ; Kooman, J.P. ; Smeulders, D.M.J./ A micro-optofluidic sensor system based on PET sensing for real time sodium concentration measurement. Proceedings of the 5th European Conference on Microfluidics. editor / Jürgen Brandner ; Stéphane Colin ; David Newport ; Christophe Serra. Paris : SHF, 2018. pp. 89-92
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title = "A micro-optofluidic sensor system based on PET sensing for real time sodium concentration measurement",
abstract = "We present a micro-optofluidic device with an integrated optical fiber to enable real time electrolyte measurements. The target application is, in-line electrolyte monitoring during dialysis. The device is fabricated in PDMS (polydimethylsiloxane) using soft-lithography. The optical sensing principle is based on selective fluorescence quenching of PET (photoinduced electron transfer) ON-OFF process. We have covalently immobilized these PET sensor molecules on the PDMS microchannel walls. A proof-of-concept device is presented for sodium concentrations measurement in a flowing medium. The first results show a clear relation between sodium concentrations and fluorescence intensity.",
author = "M.K. Sharma and A.J.H. Frijns and J.P. Kooman and D.M.J. Smeulders",
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Sharma, MK, Frijns, AJH, Kooman, JP & Smeulders, DMJ 2018, A micro-optofluidic sensor system based on PET sensing for real time sodium concentration measurement. in J Brandner, S Colin, D Newport & C Serra (eds), Proceedings of the 5th European Conference on Microfluidics. SHF, Paris, pp. 89-92, 5th European Conference on Microfluidics (µFlu’18), Strassbourg, France, 28/02/18.

A micro-optofluidic sensor system based on PET sensing for real time sodium concentration measurement. / Sharma, M.K.; Frijns, A.J.H.; Kooman, J.P.; Smeulders, D.M.J.

Proceedings of the 5th European Conference on Microfluidics. ed. / Jürgen Brandner; Stéphane Colin; David Newport; Christophe Serra. Paris : SHF, 2018. p. 89-92.

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

TY - GEN

T1 - A micro-optofluidic sensor system based on PET sensing for real time sodium concentration measurement

AU - Sharma,M.K.

AU - Frijns,A.J.H.

AU - Kooman,J.P.

AU - Smeulders,D.M.J.

PY - 2018/2/28

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N2 - We present a micro-optofluidic device with an integrated optical fiber to enable real time electrolyte measurements. The target application is, in-line electrolyte monitoring during dialysis. The device is fabricated in PDMS (polydimethylsiloxane) using soft-lithography. The optical sensing principle is based on selective fluorescence quenching of PET (photoinduced electron transfer) ON-OFF process. We have covalently immobilized these PET sensor molecules on the PDMS microchannel walls. A proof-of-concept device is presented for sodium concentrations measurement in a flowing medium. The first results show a clear relation between sodium concentrations and fluorescence intensity.

AB - We present a micro-optofluidic device with an integrated optical fiber to enable real time electrolyte measurements. The target application is, in-line electrolyte monitoring during dialysis. The device is fabricated in PDMS (polydimethylsiloxane) using soft-lithography. The optical sensing principle is based on selective fluorescence quenching of PET (photoinduced electron transfer) ON-OFF process. We have covalently immobilized these PET sensor molecules on the PDMS microchannel walls. A proof-of-concept device is presented for sodium concentrations measurement in a flowing medium. The first results show a clear relation between sodium concentrations and fluorescence intensity.

M3 - Conference contribution

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EP - 92

BT - Proceedings of the 5th European Conference on Microfluidics

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CY - Paris

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Sharma MK, Frijns AJH, Kooman JP, Smeulders DMJ. A micro-optofluidic sensor system based on PET sensing for real time sodium concentration measurement. In Brandner J, Colin S, Newport D, Serra C, editors, Proceedings of the 5th European Conference on Microfluidics. Paris: SHF. 2018. p. 89-92.