A generalized approach for automatic 3-D geometry assessment of blood vessels in transverse ultrasound images using convolutional neural networks

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Accurate 3-D geometries of arteries and veins are important clinical data for diagnosis of arterial disease and intervention planning. Automatic segmentation of vessels in the transverse view suffers from the low lateral resolution and contrast. Convolutional neural networks are a promising tool for automatic segmentation of medical images, outperforming the traditional segmentation methods with high robustness. In this study, we aim to create a general, robust, and accurate method to segment the lumen-wall boundary of healthy central and peripheral vessels in large field-of-view freehand ultrasound (US) datasets. Data were acquired using freehand US, in combination with a probe tracker. A total of ± 36000 cross-sectional images, acquired in the common, internal, and external carotid artery (N = 37), in the radial, ulnar artery, and cephalic vein (N = 12), and in the femoral artery (N = 5) were included. To create masks (of the lumen) for training data, a conventional automatic segmentation method was used. The neural networks were trained on a) data of all vessels and b) the carotid artery only. The performance was compared and tested using an open access dataset. The Recall, Precision, DICE, and the intersect-over-union (IoU) were calculated. Overall, segmentation was successful in the carotid and peripheral arteries. The Multires U-net architecture performs best overall with DICE = 0.93 when trained on the total dataset. Future studies will focus on the inclusion of vascular pathologies.

Original languageEnglish
JournalIEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
Early online date18 Jun 2021
DOIs
Publication statusE-pub ahead of print - 18 Jun 2021

Bibliographical note

Publisher Copyright:
IEEE

Keywords

  • Biomedical imaging
  • Carotid arteries
  • Convolutional Neural Network
  • Image segmentation
  • Machine Learning
  • Medical Image Segmentation
  • Probes
  • Training data
  • Ultrasonic imaging
  • Vascular Ultrasound
  • Veins

Fingerprint

Dive into the research topics of 'A generalized approach for automatic 3-D geometry assessment of blood vessels in transverse ultrasound images using convolutional neural networks'. Together they form a unique fingerprint.

Cite this