Abstract
Herein, we report the first fully automated continuous-flow platform for fluorescence quenching studies and Stern-Volmer analysis. All the components of the platform were automated and controlled by a self-written Python script. A user-friendly software allows even inexperienced operators to perform automated screening of novel quenchers or Stern-Volmer analysis, thus accelerating and facilitating both reaction discovery and mechanistic studies. The operational simplicity of our system affords a time and labor reduction over batch methods while increasing the accuracy and reproducibility of the data produced. Finally, the applicability of our platform is elucidated through relevant case studies.
| Original language | English |
|---|---|
| Pages (from-to) | 11278-11282 |
| Number of pages | 5 |
| Journal | Angewandte Chemie - International Edition |
| Volume | 57 |
| Issue number | 35 |
| DOIs | |
| Publication status | Published - 27 Aug 2018 |
Keywords
- Automation
- Continuous flow
- Fluorescence quenching experiments
- Photoredox catalysis
- Stern-Volmer
- continuous flow
- automation
- fluorescence quenching experiments
- Stern–Volmer
- photoredox catalysis