Abstract
Herein, we report the first fully automated continuous-flow platform for fluorescence quenching studies and Stern-Volmer analysis. All the components of the platform were automated and controlled by a self-written Python script. A user-friendly software allows even inexperienced operators to perform automated screening of novel quenchers or Stern-Volmer analysis, thus accelerating and facilitating both reaction discovery and mechanistic studies. The operational simplicity of our system affords a time and labor reduction over batch methods while increasing the accuracy and reproducibility of the data produced. Finally, the applicability of our platform is elucidated through relevant case studies.
Original language | English |
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Pages (from-to) | 11278-11282 |
Number of pages | 5 |
Journal | Angewandte Chemie - International Edition |
Volume | 57 |
Issue number | 35 |
DOIs | |
Publication status | Published - 27 Aug 2018 |
Keywords
- Automation
- Continuous flow
- Fluorescence quenching experiments
- Photoredox catalysis
- Stern-Volmer
- continuous flow
- automation
- fluorescence quenching experiments
- Stern–Volmer
- photoredox catalysis