This article shows that the first step towards the miniaturization of HPLC systems can be made without any, or only slight, modification to conventional equipment. Minor (less expensive) equipment modifications, particularly the use of micro-detector cells, allow the routine use of 3.2- and 2.1-mm i.d. small-bore columns in isocratic as well as gradient mode. This work encourages analysts to take a step towards the introduction of miniaturized HPLC systems in their laboratories, resulting in a considerable reduction in the use and costs of organic solvents and the establishment of "greener" laboratories.
|Pages (from-to)||42, 44-46, 48, 50|
|Journal||LC-GC International : the Magazine of Separation Science|
|Publication status||Published - 1996|
Straten, van, M. A., Vermeer, E. A., & Claessens, H. A. (1996). A first step towards miniaturized HPLC systems in analytical routine laboratories. LC-GC International : the Magazine of Separation Science, 42, 44-46, 48, 50.