A Femto-Ampere sensitive direct-interface current-input sigma delta ADC for Amperometric bio-sensor signal acquisition

K.J. Pol, S.F. Ouzounov, J.A. Hegt, A.H.M. van Roermund

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

6 Citations (Scopus)
2 Downloads (Pure)

Abstract

In this paper we present an ultra-low current measurement platform for amperometric bio-sensor readout. A current mode continuous-time sigma delta ADC is implemented and used as a direct interface to the bio-sensor, thereby omitting any intermediate frontend circuitry. This results in a low noise
and low power readout suitable for compact integration. The ADC is reconfigurable and has a programmable dynamic range extending from 25nA to 250uA, along with a scalable clock allowing different conversion times. The wide dynamic range supports a variety of applications ranging from solid-state nanopores (pA), carbon nanotubes (nA) and certain protein based electrochemical bio-sensors (uA). Measurements show an integrated noise current of 314fA in a 100 Hz bandwidth, resulting in a resolution of 19-bit. The chip dissipates 1.7mW and achieves a FOM of 162.6 dB.
Original languageEnglish
Title of host publication2015 IEEE Biomedical Circuits and Systems Conference (BioCAS), 22-24 October 2015, Atlanta, Georgia
Place of PublicationPiscataway
PublisherInstitute of Electrical and Electronics Engineers
Pages1-4
DOIs
Publication statusPublished - 22 Oct 2015

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