A damage threshold for skeletal muscle under sustained mechanical loading

C.W.J. Oomens, A. Stekelenburg, K.K. Ceelen, D.L. Bader

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Abstract

Since people started to study the aetiology of pressure ulcers, an important objective has been to identify a damage threshold to predict, how much mechanical loading the tissues can sustain before damage is initiated. Many experimental as well as patient-related studies have been performed to find such a threshold, but they have been largely limited as they compared global external loads with a vague description of internal damage. The present chapter describes the investigations at Eindhoven University of Technology to find a threshold, which is a property. Such a threshold should be generic in nature, in the sense that it could be used as a predictive property for different experimental configurations and in the clinical setting.
Original languageEnglish
Title of host publicationThe pathomechanics of tissue injury and disease, and the mechanophysiology of healing
EditorsA. Gefen
Place of PublicationKarela
PublisherResearch Signpost
Pages313-326
ISBN (Print)978-81-308-0314-2
Publication statusPublished - 2009

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    Oomens, C. W. J., Stekelenburg, A., Ceelen, K. K., & Bader, D. L. (2009). A damage threshold for skeletal muscle under sustained mechanical loading. In A. Gefen (Ed.), The pathomechanics of tissue injury and disease, and the mechanophysiology of healing (pp. 313-326). Research Signpost.