A composition-based cartilage model for the assessment of compositional changes during cartilage damage and adaptation

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Abstract

The composition of articular cartilage changes with progression of osteoarthritis. Since compositional changes are associated with changes in the mechanical properties of the tissue, they are relevant for understanding how mechanical loading induces progression. The objective of this study is to present a computational model of articular cartilage which enables to study the interaction between composition and mechanics.
Original languageEnglish
Pages (from-to)554-560
JournalOsteoarthritis and Cartilage
Volume14
Issue number6
DOIs
Publication statusPublished - 2006

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