TY - JOUR
T1 - A centrifuge method to determine the solid–liquid phase behavior of eutectic mixtures
AU - van den Bruinhorst, Adriaan
AU - Kollau, Laura J.B.M.
AU - Kroon, Maaike C.
AU - Meuldijk, Jan
AU - Tuinier, Remco
AU - Esteves, A. Catarina C.
PY - 2018/12/14
Y1 - 2018/12/14
N2 - The centrifuge method is a novel, equilibrium-based, analytical procedure that allows the construction of solid–liquid phase diagrams of binary eutectic mixtures. In this paper, the development, optimization, and successful verification of the centrifuge method are described. Contrary to common dynamic analysis techniques—differential scanning calorimetry and hot-stage microscopy—the studied mixtures are equilibrated at constant temperature. Therefore, the mixtures do not need to be recrystallized from the melt during analysis. This offers a great advantage for mixtures that exhibit strong supercooling behavior rather than direct crystallization. The centrifuge method was verified by reproducing the binary eutectic phase behavior of both the nearly ideal biphenyl–bibenzyl system and the strongly non-ideal deep eutectic solvent (DES) urea–choline chloride, which is prone to supercooling. Hence, the centrifuge method offers an alternative route to common dynamic analysis techniques for the quantification of the liquid range of DESs and other binary eutectic mixtures.
AB - The centrifuge method is a novel, equilibrium-based, analytical procedure that allows the construction of solid–liquid phase diagrams of binary eutectic mixtures. In this paper, the development, optimization, and successful verification of the centrifuge method are described. Contrary to common dynamic analysis techniques—differential scanning calorimetry and hot-stage microscopy—the studied mixtures are equilibrated at constant temperature. Therefore, the mixtures do not need to be recrystallized from the melt during analysis. This offers a great advantage for mixtures that exhibit strong supercooling behavior rather than direct crystallization. The centrifuge method was verified by reproducing the binary eutectic phase behavior of both the nearly ideal biphenyl–bibenzyl system and the strongly non-ideal deep eutectic solvent (DES) urea–choline chloride, which is prone to supercooling. Hence, the centrifuge method offers an alternative route to common dynamic analysis techniques for the quantification of the liquid range of DESs and other binary eutectic mixtures.
U2 - 10.1063/1.5051515
DO - 10.1063/1.5051515
M3 - Article
C2 - 30553256
SN - 0021-9606
VL - 149
JO - Journal of Chemical Physics
JF - Journal of Chemical Physics
IS - 22
M1 - 224505
ER -