A 62Zn/62Cu generator for the routine production of 62Cu-PTSM

G. Bormans; A.G.M. Janssen; P. Adriaens; D. Crombez; A.J. Witsenboer; J.J.M. de Goeij; L. Mortelmans; A. Verbruggen

doi:10.1016/0883-2889(92)90169-F

A 62Zn/62Cu generator for the routine production of 62Cu-PTSM

G. Bormans, A.G.M. Janssen, P. Adriaens, D. Crombez, A.J. Witsenboer, J.J.M. de Goeij, L. Mortelmans, A. Verbruggen

Applied Physics and Science Education

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

We have developed an improved 62Cu-generator system based on a small (25 mm × 5 mm) ion exchange column which allows the instant production of 62Cu-PTSM ready for injection. The generator column can rapidly be eluted with a high yield in a volume of 1 mL to afford an eluate with largely acceptable radionuclidic purity. Collection of the eluate in a labelling kit which contains the PTSM ligand in an appropriate buffer allows to obtain in less than 30 s a highly pure 62Cu-PTSM preparation that can be injected intravenously.

Original language	English
Pages (from-to)	1437-1441
Journal	Applied Radiation and Isotopes
Volume	43
Issue number	12
DOIs	https://doi.org/10.1016/0883-2889(92)90169-F
Publication status	Published - 1992

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title = "A 62Zn/62Cu generator for the routine production of 62Cu-PTSM",

abstract = "We have developed an improved 62Cu-generator system based on a small (25 mm × 5 mm) ion exchange column which allows the instant production of 62Cu-PTSM ready for injection. The generator column can rapidly be eluted with a high yield in a volume of 1 mL to afford an eluate with largely acceptable radionuclidic purity. Collection of the eluate in a labelling kit which contains the PTSM ligand in an appropriate buffer allows to obtain in less than 30 s a highly pure 62Cu-PTSM preparation that can be injected intravenously.",

author = "G. Bormans and A.G.M. Janssen and P. Adriaens and D. Crombez and A.J. Witsenboer and {de Goeij}, J.J.M. and L. Mortelmans and A. Verbruggen",

year = "1992",

doi = "10.1016/0883-2889(92)90169-F",

language = "English",

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journal = "Applied Radiation and Isotopes",

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TY - JOUR

T1 - A 62Zn/62Cu generator for the routine production of 62Cu-PTSM

AU - Bormans, G.

AU - Janssen, A.G.M.

AU - Adriaens, P.

AU - Crombez, D.

AU - Witsenboer, A.J.

AU - de Goeij, J.J.M.

AU - Mortelmans, L.

AU - Verbruggen, A.

PY - 1992

Y1 - 1992

N2 - We have developed an improved 62Cu-generator system based on a small (25 mm × 5 mm) ion exchange column which allows the instant production of 62Cu-PTSM ready for injection. The generator column can rapidly be eluted with a high yield in a volume of 1 mL to afford an eluate with largely acceptable radionuclidic purity. Collection of the eluate in a labelling kit which contains the PTSM ligand in an appropriate buffer allows to obtain in less than 30 s a highly pure 62Cu-PTSM preparation that can be injected intravenously.

AB - We have developed an improved 62Cu-generator system based on a small (25 mm × 5 mm) ion exchange column which allows the instant production of 62Cu-PTSM ready for injection. The generator column can rapidly be eluted with a high yield in a volume of 1 mL to afford an eluate with largely acceptable radionuclidic purity. Collection of the eluate in a labelling kit which contains the PTSM ligand in an appropriate buffer allows to obtain in less than 30 s a highly pure 62Cu-PTSM preparation that can be injected intravenously.

U2 - 10.1016/0883-2889(92)90169-F

DO - 10.1016/0883-2889(92)90169-F

M3 - Article

SN - 0969-8043

VL - 43

SP - 1437

EP - 1441

JO - Applied Radiation and Isotopes

JF - Applied Radiation and Isotopes

IS - 12

ER -

A 62Zn/62Cu generator for the routine production of 62Cu-PTSM

Abstract

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