Find Research Output

Search concepts
Selected filters

Publication Year

  • 2020
  • 2019
  • 2018
  • 2017
  • 2016

Author

  • Jan C.M. Hest, van
2020

Biomimicry of Cellular Motility and Communication Based on Synthetic Soft-Architectures

Wang, L., Song, S., van Hest, J., Abdelmohsen, L. K. E. A., Huang, X. & Sánchez, S., 6 Apr 2020, In : Small.

Research output: Contribution to journalReview articleAcademicpeer-review

CD44-targeted vesicles encapsulating granzyme B as artificial killer cells for potent inhibition of human multiple myeloma in mice

Zhong, Y., Meng, F., Zhang, W., Li, B., van Hest, J. C. M. & Zhong, Z., 10 Apr 2020, In : Journal of Controlled Release. 320, p. 421-430 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Compartmentalized cross-linked enzymatic nano -aggregates (c -CLE n A) for efficient in-flow biocatalysis

de Martino, M. T., Tonin, F., Yewdall, N. A., Abdelghani, M., Williams, D. S., Hanefeld, U., Rutjes, F. P. J. T., Abdelmohsen, L. K. E. A. & van Hest, J. C. M., 14 Mar 2020, In : Chemical Science. 11, 10, p. 2765-2769 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
8 Downloads (Pure)

Hyperthermia-Triggered On-Demand Biomimetic Nanocarriers for Synergetic Photothermal and Chemotherapy

Gao, J., Wang, F., Wang, S., Liu, L., Liu, K., Ye, Y., Wang, Z., Wang, H., Chen, B., Jiang, J., Ou, J., van Hest, J. C. M., Peng, F. & Tu, Y., 1 Jan 2020, (Accepted/In press) In : Advanced Science.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Influence of surface charge on the formulation of elongated PEG-b-PDLLA nanoparticles

Ridolfo, R., Williams, D. S. & van Hest, J. C. M., 28 Apr 2020, In : Polymer Chemistry. 11, 16, p. 2775-2780 6 p.

Research output: Contribution to journalArticleAcademic

Open Access

Intercellular communication between artificial cells by allosteric amplification of a molecular signal

Buddingh', B. C., Elzinga, J. & van Hest, J. C. M., 3 Apr 2020, In : Nature Communications. 11, 1, 10 p., 1652.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
10 Downloads (Pure)
Open Access
File
2 Citations (Scopus)
14 Downloads (Pure)

Multifunctional PVCL nanogels with redox-responsiveness enable enhanced MR imaging and ultrasound-promoted tumor chemotherapy

Xu, F., Zhu, J., Lin, L., Zhang, C., Sun, W., Fan, Y., Yin, F., van Hest, J. C. M., Wang, H., Du, L. & Shi, X., 1 Jan 2020, In : Theranostics. 10, 10, p. 4349-4358 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Pathway dependent shape-transformation of azide-decorated polymersomes

Che, H., de Windt, L. N. J., Zhu, J., Pijpers, I. A. B., Mason, A. F., Abdelmohsen, L. K. E. A. & van Hest, J. C. M., 18 Feb 2020, In : Chemical Communications. 56, 14, p. 2127-2130 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
9 Downloads (Pure)

Screening of functional solvent system for automatic aldehyde and ketone separation in aldol reaction: a combined COSMO-RS and experimental approach

Zhang, C., Song, Z., Jin, C., Nijhuis, J., Zhou, T., Noël, T., Gröger, H., Sundmacher, K., van Hest, J. & Hessel, V., 1 Apr 2020, In : Chemical Engineering Journal. 385, 10 p., 123399.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
28 Downloads (Pure)

Supramolecular nanoscaffolds within cytomimetic protocells as signal localization hubs

Magdalena Estirado, E., Mason, A. F., Garcia, M. A., van Hest, J. C. M. & Brunsveld, L., 20 May 2020, In : Journal of the American Chemical Society. 142, 20, p. 9106-9111 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Synthetic pathways to tetrahydrocannabinol (THC): an overview

Bloemendal, V. R. L. J., van Hest, J. C. M. & Rutjes, F. P. J. T., 7 May 2020, In : Organic and Biomolecular Chemistry. 18, 17, p. 3203-3215 13 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Wormlike nanovector with enhanced drug loading using blends of biodegradable block copolymers

Ridolfo, R., Arends, J. J., van Hest, J. C. M. & Williams, D. S., 8 Apr 2020, In : Biomacromolecules.

Research output: Contribution to journalArticleAcademic

α3β1 Integrin-Targeting Polymersomal Docetaxel as an Advanced Nanotherapeutic for Nonsmall Cell Lung Cancer Treatment

Zou, Y., Sun, Y., Guo, B., Wei, Y., Xia, Y., Huangfu, Z., Meng, F., van Hest, J. C. M., Yuan, J. & Zhong, Z., 1 Apr 2020, In : ACS Applied Materials and Interfaces. 12, 13, p. 14905-14913 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

2019

Adaptive polymeric assemblies for applications in biomimicry and nanomedicine

Altay, Y., Che, H., Cao, S., Abdelmohsen, L. & van Hest, J., 11 Nov 2019, In : Biomacromolecules. 20, 11, p. 4053-4064 12 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
File
3 Citations (Scopus)
34 Downloads (Pure)

Adaptive polymersome nanoreactors

Che, H. & van Hest, J. C. M., 1 Sep 2019, In : ChemNanoMat. 5, 9, p. 1092-1109 18 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
3 Citations (Scopus)
52 Downloads (Pure)

Alendronate-functionalized poly(2-oxazoline)s with tunable affinity for calcium cations

Sánchez-Fernández, M. J., Immers, M. R., Félix Lanao, R. P., Yang, F., Bender, J. C. M. E., Mecinović, J., Leeuwenburgh, S. C. G. & van Hest, J. C. M., 12 Aug 2019, In : Biomacromolecules. 20, 8, p. 2913-2921 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
11 Downloads (Pure)

A revised modular approach to (–)-trans-Δ 8 -THC and derivatives through late-stage Suzuki–Miyaura cross-coupling reactions

Bloemendal, V. R. L. J., Sondag, D., Elferink, H., Boltje, T. J., van Hest, J. C. M. & Rutjes, F. P. J. T., 31 Mar 2019, In : European Journal of Organic Chemistry. 2019, 12, p. 2289-2296 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
3 Citations (Scopus)
30 Downloads (Pure)

ATP-mediated transient behavior of stomatocyte nanosystems

Che, H., Zhu, J., Song, S., Mason, A. F., Cao, S., Pijpers, I. A. B., Abdelmohsen, L. K. E. A. & van Hest, J. C. M., 9 Sep 2019, In : Angewandte Chemie - International Edition. 58, 37, p. 13113-13118 6 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
File
5 Citations (Scopus)
3 Downloads (Pure)

Biomorphic engineering of multifunctional polylactide stomatocytes toward therapeutic nano-red blood cells

Shao, J., Pijpers, I. A. B., Cao, S., Williams, D. S., Yan, X., Li, J., Abdelmohsen, L. K. E. A. & van Hest, J. C. M., 6 Mar 2019, In : Advanced Science. 6, 5, 8 p., 1801678.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
5 Citations (Scopus)
32 Downloads (Pure)

Bone-adhesive materials: clinical requirements, mechanisms of action, and future perspective

Sánchez-Fernández, M. J., Hammoudeh, H., Félix Lanao, R. P., van Erk, M., van Hest, J. C. M. & Leeuwenburgh, S. C. G., 22 Feb 2019, In : Advanced Materials Interfaces. 6, 4, 11 p., 1802021.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
File
3 Citations (Scopus)
38 Downloads (Pure)

Cell-free microcompartmentalised transcription-translation for the prototyping of synthetic communication networks

Dubuc, E., Pieters, P. A., van der Linden, A. J., van Hest, J. C. M., Huck, W. T. S. & de Greef, T. F. A., 1 Aug 2019, In : Current Opinion in Biotechnology. 58, p. 72-80 9 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
File
10 Citations (Scopus)
75 Downloads (Pure)

Chemoenzymatic synthesis of sialic acid derivatives using immobilized N-acetylneuraminate lyase in a continuous flow reactor

Bloemendal, V. R. L. J., Moons, S. J., Heming, J. J. A., Chayoua, M., Niesink, O., van Hest, J. C. M., Boltje, T. J. & Rutjes, F. P. J. T., 6 Jun 2019, In : Advanced Synthesis & Catalysis. 361, 11, p. 2443-2447 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
5 Downloads (Pure)

Development of morphologically discrete PEG-PDLLA nanotubes for precision nanomedicine

Wauters, A. C., Pijpers, I. A. B., Mason, A. F., Williams, D. S., Tel, J., Abdelmohsen, L. K. E. A. & van Hest, J. C. M., 14 Jan 2019, In : Biomacromolecules. 20, 1, p. 177-183 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
5 Citations (Scopus)
76 Downloads (Pure)

Dynamic assembly of micellar mesostructures

Altay, Y., Pijpers - Welzen, I., Abdelmohsen, L. & van Hest, J., 28 Oct 2019, In : ChemSystemsChem. 2, 2, 5 p., e1900049.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
3 Downloads (Pure)
Open Access
File
7 Citations (Scopus)
28 Downloads (Pure)

Molecular programming of biodegradable nanoworms via ionically induced morphology switch toward asymmetric therapeutic carriers

Cao, S., Shao, J., Xia, Y., Che, H., Zhong, Z., Meng, F., van Hest, J. C. M., Abdelmohsen, L. K. E. A. & Williams, D. S., 1 Sep 2019, In : Small. 15, 38, 8 p., 1901849.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
4 Citations (Scopus)
31 Downloads (Pure)

Multifaceted cell mimicry in coacervate-based synthetic cells

Mason, A. & Hest, van, J. C. M., Nov 2019, In : Emerging Topics in Life Sciences. 3, 5, p. 567-571 5.

Research output: Contribution to journalArticleAcademicpeer-review

Myosin II isoforms play distinct roles in adherens junction biogenesis

Heuzé, M. L., Sankara Narayana, G. H. N., D'Alessandro, J., Cellerin, V., Dang, T., Williams, D. S., van Hest, J. C. M., Marcq, P., Mège, R. M. & Ladoux, B., 5 Sep 2019, In : eLife. 8, 30 p., e46599.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
5 Citations (Scopus)
148 Downloads (Pure)

Octa-arginine boosts the penetration of elastin-like polypeptide nanoparticles in 3D cancer models

van Oppen, L. M. P. E., Pille, J., Stuut, C., van Stevendaal, M., van der Vorm, L. N., Smeitink, J. A. M., Koopman, W. J. H., Willems, P. H. G. M., van Hest, J. C. M. & Brock, R., 1 Apr 2019, In : European Journal of Pharmaceutics and Biopharmaceutics. 137, p. 175-184 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

5 Citations (Scopus)
1 Downloads (Pure)

Physicochemical characterization of polymer-stabilized coacervate protocells

Yewdall, N. A., Buddingh, B. C., Altenburg, W. J., Timmermans, S. B. P. E., Vervoort, D. F. M., Abdelmohsen, L. K. E. A., Mason, A. F. & van Hest, J., 15 Oct 2019, In : ChemBioChem. 20, 20, p. 2643-2652 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
2 Citations (Scopus)
18 Downloads (Pure)

Scale-up of the manufacturing process to produce docetaxel-loaded mPEG- b-p(HPMA-Bz) block copolymer micelles for pharmaceutical applications

Bresseleers, J., Bagheri, M., Storm, G., Metselaar, J. M., Hennink, W. E., Meeuwissen, S. A. & van Hest, J. C. M., 20 Dec 2019, In : Organic Process Research and Development. 23, 12, p. 2707-2715 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
10 Downloads (Pure)

Single enzyme loaded nanoparticles for combinational ultrasound-guided focused ultrasound ablation and hypoxia-relieved chemotherapy

Zhu, J., Li, Z., Zhang, C., Lin, L., Cao, S., Che, H., Shi, X., Wang, H. & van Hest, J. C. M., 1 Jan 2019, In : Theranostics. 9, 26, p. 8048-8060 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
2 Citations (Scopus)
16 Downloads (Pure)

Versatile reversible cross-linking strategy to stabilize CCMV virus like particles for efficient siRNA delivery

Pretto, C. & van Hest, J. C. M., 18 Dec 2019, In : Bioconjugate Chemistry. 30, 12, p. 3069-3077 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
21 Downloads (Pure)
2018

Adaptive polymersome and micelle morphologies in anticancer nanomedicine: from design rationale to fabrication and proof-of-concept studies

Pijpers, I. A. B., Abdelmohsen, L. K. E. A., Xia, Y., Cao, S., Williams, D. S., Meng, F., van Hest, J. C. M. & Zhong, Z., 1 Dec 2018, In : Advanced Therapeutics. 1, 8, 14 p., 1800068.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
3 Downloads (Pure)

A filter-free blood-brain barrier model to quantitatively study transendothelial delivery of nanoparticles by fluorescence spectroscopy

De Jong, E., Williams, D. S., Abdelmohsen, L. K. E. A., van Hest, J. C. M. & Zuhorn, I. S., 10 Nov 2018, In : Journal of Controlled Release. 289, p. 14-22 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
1 Citation (Scopus)
38 Downloads (Pure)

Biodegradable, drug-loaded nanovectors via direct hydration as a new platform for cancer therapeutics

Ridolfo, R., Ede, B. C., Diamanti, P., White, P. B., Perriman, A. W., van Hest, J. C. M., Blair, A. & Williams, D. S., 9 Aug 2018, In : Small. 14, 32, 10 p., 1703774.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
4 Citations (Scopus)
52 Downloads (Pure)

Biodegradable synthetic organelles demonstrate ROS shielding in human-complex-I-deficient fibroblasts

van Oppen, L. M. P. E., Abdelmohsen, L. K. E. A., van Emst-de Vries, S. E., Welzen, P. L. W., Wilson, D. A., Smeitink, J. A. M., Koopman, W. J. H., Brock, R., Willems, P. H. G. M., Williams, D. S. & van Hest, J. C. M., 25 Jul 2018, In : ACS Central Science. 4, 7, p. 917-928 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
12 Citations (Scopus)
84 Downloads (Pure)

Chemical tools and materials for Biological/Medicinal applications

Yan, X. & van Hest, J. C. M., 16 Nov 2018, In : Chemistry - An Asian Journal. 13, 22, p. 3331-3332 2 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access
6 Citations (Scopus)

Copolymer-stabilized coacervate microdroplets as multicompartmentalized artificial cells

Mason, A., Abdelmohsen, L., Yewdall, N. A., Buddingh, B., Williams, D. & van Hest, J., Aug 2018, In : Abstracts of Papers of the American Chemical Society. 1 p., BM09.12.07.

Research output: Contribution to journalMeeting AbstractAcademic

Open Access
File
31 Downloads (Pure)

Editorial 2018

van Hest, J., Lavik, E. B., Smith, B. D., Zheng, G. & Rotello, V. M., 17 Jan 2018, In : Bioconjugate Chemistry. 29, 1, p. 1-3 3 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access

Effect of formulation and processing parameters on the size of mPEG-b-p(HPMA-Bz) polymeric micelles

Bagheri, M., Bresseleers, J., Varela-Moreira, A., Sandre, O., Meeuwissen, S. A., Schiffelers, R. M., Metselaar, J. M., Van Nostrum, C. F., van Hest, J. C. M. & Hennink, W. E., 18 Dec 2018, In : Langmuir. 34, 50, p. 15495-15506 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Scopus)
1 Downloads (Pure)

Engineering protein-based nanoparticle conjugates for nanomedicine applications

van Hest, J., Pille, J., Abdelghani, M., Timmermans, S., Vervoort, D. & Pretto, C., 19 Aug 2018, 256th National Meeting and Exposition of the American-Chemical-Society (ACS) - Nanoscience, Nanotechnology and Beyond .

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Erythrocyte membrane modified janus polymeric motors for thrombus therapy

Shao, J., Abdelghani, M., Shen, G., Cao, S., Williams, D. S. & van Hest, J. C. M., 22 May 2018, In : ACS Nano. 12, 5, p. 4877-4885 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
28 Citations (Scopus)
64 Downloads (Pure)

Feedback-induced temporal control of “breathing” polymersomes to create self-adaptive nanoreactors

Che, H., Cao, S. & van Hest, J. C. M., 25 Apr 2018, In : Journal of the American Chemical Society. 140, 16, p. 5356–5359 4 p., 16.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
42 Citations (Scopus)
113 Downloads (Pure)

Metal ion-induced self-assembly and packaging of CCMV nanocapsules

Schoonen, L., van Eldijk, M. B. & van Hest, J. C. M., 5 Jun 2018, Protein scaffolds: design, synthesis, and applications. Udit, A. K. (ed.). Dordrecht: Springer, p. 57-67 11 p. (Methods in Molecular Biology; vol. 1798).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

1 Citation (Scopus)

Modification of CCMV nanocages for enzyme encapsulation

Schoonen, L. & van Hest, J. C. M., 5 Jun 2018, Protein Scaffolds : Design, Synthesis, and Applications. Udit, A. K. (ed.). Dordrecht: Springer, p. 69-83 15 p. (Methods in Molecular Biology; vol. 1798).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

1 Citation (Scopus)

Modular, bioorthogonal strategy for the controlled loading of cargo into a protein nanocage

Schoonen, L., Eising, S., van Eldijk, M. B., Bresseleers, J., Van Der Pijl, M., Nolte, R. J. M., Bonger, K. M. & van Hest, J. C. M., 18 Apr 2018, In : Bioconjugate Chemistry. 29, 4, p. 1186-1193 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
4 Citations (Scopus)
77 Downloads (Pure)

Nanoreactors for green catalysis

De Martino, M. T., Abdelmohsen, L. K. E. A., Rutjes, F. P. J. T., van Hest, J. C. M. & Hessel, V. (Guest ed.), 29 Mar 2018, In : Beilstein Journal of Organic Chemistry. 14, p. 716–733 18 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
19 Citations (Scopus)
108 Downloads (Pure)

PH-induced transformation of biodegradable multilamellar nanovectors for enhanced tumor penetration

Cao, S., Abdelmohsen, L. K. E. A., Shao, J., van den Dikkenberg, J., Mastrobattista, E., Williams, D. S. & van Hest, J. C. M., 20 Nov 2018, In : ACS Macro Letters. 7, 11, p. 1394-1399 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
7 Citations (Scopus)
48 Downloads (Pure)