4D coronary artery reconstruction based on retrospectively gated rotational angiography: first in-human results

B. Movassaghi, M. Grass, D. Schaefer, V. Rasche, O. Wink, G.A.F. Schoonenberg, S.Y.J. Chen, J.A. Garcia, B. Groves, J.C. Messenger, J.D. Carroll

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

11 Citations (Scopus)


A method is proposed that allows for a fully automated computation of a series of high-resolution volumetric reconstructions of a patient's coronary arteries based on a single rotational acquisition. During the 7.2 second acquisition the coronary arteries are injected with contrast material while the imaging system rotates around the patient to obtain a series of X-ray projection images over an angular range of 180 degrees. Based on the simultaneously recorded ECG-signal the projection images corresponding to the same cardiac cycle can be utilized to reconstruct three-dimensional (3D) high-spatial-resolution angiograms of the coronary arteries in multiple (3D+t) cardiac phases within the cardiac cycle. The proposed acquisition protocol has been applied to 22 patients and the tomograpic reconstructions depicted the main arteries as well as the main bifurcations in multiple cardiac phases in all enrolled patients. For the first time, this feasibility study shows that a three-dimensional description of the coronary arteries can be obtained intraprocedurally in a conventional interventional suite by means of tomographic reconstruction from projection images without any user interaction.
Original languageEnglish
Title of host publicationSPIE Medical Imaging 2007: Visualization and Image-Guided Procedure, United States, San Diego, CA
EditorsKevin R. Cleary, Michael I. Miga
Place of PublicationBellingham
Number of pages6
Publication statusPublished - 2007

Publication series

NameProceedings of SPIE
ISSN (Print)1605-7422


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