Piloting cascaded continuous flow synthesis for the pharmaceutical industry

  • Hessel, V. (Recipient)

Prize: ERCProof of conceptScientific


PICASCO aims to deliver the commercial proof of concept of a novel endto- end flow manufacturing and a novel corresponding compact flow mini plant. This is performed through the first continuous 4-step solvent-free flow manufacturing of a pharmaceutically relevant API compound at an industrial scale. Currently applied batch manufacturing techniques leave much room for improved quality, efficiency, cost-effectiveness and environmental friendliness. Flow multi-step manufacturing can address all these issues simultaneously, but to date has not been brought to an industrially useful scale. PICASCO sets out to scale this final barrier.
Degree of recognitionInternational
Granting OrganisationsEuropean Research Council