Catalysis – the workhorse of chemical industry – accounts for more than 90% of commercial chemicals. Design of more efficient catalytic materials is the core challenge faced by catalysis science in coming era of sustainable chemistry. In this project a new concept of force-responsive heterogeneous catalysis will be explored. Ultra-flexible graphene frameworks modified with palladium nanoparticles will be used as catalysts for CO2 hydrogenation. The pore size of these materials and hypothetically their catalytic properties can be reversibly fine-tuned by applying external mechanical force. The proposed concept might open unprecedented opportunities for controlling the rate and selectivity of catalytic reactions.