• 13 Citations
20182019
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Research Output 2018 2019

  • 13 Citations
  • 7 Article
  • 1 Inaugural speech
  • 1 Phd Thesis 2 (Research NOT TU/e / Graduation TU/e)
2019

Androgen receptor genomics for patient stratification: from biomarker discovery to mechanisms

Stelloo, S., 1 Jul 2019, Eindhoven: Technische Universiteit Eindhoven. 291 p.

Research output: ThesisPhd Thesis 2 (Research NOT TU/e / Graduation TU/e)Academic

1 Citation (Scopus)

CHD1 loss alters AR binding at lineage-specific enhancers and modulates distinct transcriptional programs to drive prostate tumorigenesis

Augello, M. A., Liu, D., Deonarine, L. D., Robinson, B. D., Huang, D., Stelloo, S., Blattner, M., Doane, A. S., Wong, E. W. P., Chen, Y., Rubin, M. A., Beltran, H., Elemento, O., Bergman, A. M., Zwart, W., Sboner, A., Dephoure, N. & Barbieri, C. E., 15 Apr 2019, In : Cancer Cell. 35, 4, p. 603-617

Research output: Contribution to journalArticleAcademicpeer-review

Androgen Receptors
Prostate
Carcinogenesis
Neoplasms
Prostatic Neoplasms

GATA3 truncating mutations promote cistromic re-programming in vitro, but not mammary tumor formation in mice

Cornelissen, L. M., de Bruijn, R., Henneman, L., Kim, Y., Zwart, W. & Jonkers, J., 19 Jun 2019, In : Journal of Mammary Gland Biology and Neoplasia.

Research output: Contribution to journalArticleAcademicpeer-review

Human Mammary Glands
Breast Neoplasms
Mutation
GATA3 Transcription Factor
Zinc Fingers

Het fundament van maatwerk

Zwart, W., 10 May 2019, Eindhoven: Technische Universiteit Eindhoven. 32 p.

Research output: Book/ReportInaugural speechAcademic

Open Access
File
1 Citation (Scopus)

Optimized ChIP-seq method facilitates transcription factor profiling in human tumors

Singh, A. A., Schuurman, K., Nevedomskaya, E., Stelloo, S., Linder, S., Droog, M., Kim, Y., Sanders, J., van der Poel, H., Bergman, A. M., Wessels, L. F. A. & Zwart, W., 1 Jan 2019, In : Life Science Alliance. 2, 1, 12 p., e201800115

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Chromatin Immunoprecipitation
tumor
Chromatin
chromatin
Tumors
2018
2 Citations (Scopus)

Enzalutamide therapy for advanced prostate cancer: efficacy, resistance and beyond

Linder, S., van der Poel, H. G., Bergman, A. M., Zwart, W. & Prekovic, S., 31 Oct 2018, In : Endocrine-related cancer. 26, 1, p. R31-R52 22 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Prostatic Neoplasms
Castration
Therapeutics
Androgen Receptor Antagonists
Translational Medical Research
3 Citations (Scopus)

FOXA1 levels are decreased in pleural breast cancer metastases after adjuvant endocrine therapy, and this is associated with poor outcome

Schrijver, W., Schuurman, K., van Rossum, A., Droog, M., Jeronimo, C., Salta, S., Henrique, R., Wesseling, J., Moelans, C., Linn, S. C., van den Heuvel, M., van Diest, P. & Zwart, W., Nov 2018, In : Molecular Oncology. 12, 11, p. 1884-1894 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Breast Neoplasms
Neoplasm Metastasis
Cell Proliferation
Therapeutics
Neoplasms
3 Citations (Scopus)

Integrative epigenetic taxonomy of primary prostate cancer

Stelloo, S., Nevedomskaya, E., Kim, Y., Schuurman, K., Valle-Encinas, E., Lobo, J., Krijgsman, O., Peeper, D. S., Chang, S. L., Feng, F. Y. C., Wessels, L. F. A., Henrique, R., Jerónimo, C., Bergman, A. M. & Zwart, W., 21 Nov 2018, In : Nature Communications. 9, 1, 1 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
taxonomy
Androgen Receptors
Taxonomies
Epigenomics
Prostatic Neoplasms
3 Citations (Scopus)

Molecular underpinnings of enzalutamide resistance

Prekovic, S., van den Broeck, T., Linder, S., van Royen, M. E., Houtsmuller, A. B., Handle, F., Joniau, S., Zwart, W. & Claessens, F., 1 Nov 2018, In : Endocrine-related cancer. 25, 11, p. R545-R557 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Prostatic Neoplasms
Androgen Receptors
Second Primary Neoplasms
Therapeutics
Hormones