Content available in repository
Content available in repository
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
External positions
Nederlands Kanker Instituut - AVL
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Androgen receptor reprogramming demarcates prognostic, context-dependent gene sets in primary and metastatic prostate cancer
Severson, T., Qiu, X., Alshalalfa, M., Sjöström, M., Quigley, D., Bergman, A., Long, H., Feng, F., Freedman, M. L., Zwart, W. & Pomerantz, M. M., 4 May 2022, In: Clinical Epigenetics. 14, 1, 6 p., 60.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile2 Citations (Scopus)7 Downloads (Pure) -
Drug-Induced Epigenomic Plasticity Reprograms Circadian Rhythm Regulation to Drive Prostate Cancer toward Androgen Independence
Linder, S., Hoogstraat, M., Stelloo, S., Eickhoff, N., Schuurman, K., de Barros, H., Alkemade, M., Bekers, E. M., Severson, T. M., Sanders, J., Huang, C. C. F., Morova, T., Altintas, U. B., Hoekman, L., Kim, Y., Baca, S. C., Sjöström, M., Zaalberg, A., Hintzen, D. C., de Jong, J., & 16 others, 1 Sep 2022, In: Cancer Discovery. 12, 9, p. 2074-2097 24 p.Research output: Contribution to journal › Article › Academic › peer-review
5 Citations (Scopus) -
Extensive androgen receptor enhancer heterogeneity in primary prostate cancers underlies transcriptional diversity and metastatic potential
Kneppers, J., Severson, T. M., Siefert, J. C., Schol, P., Joosten, S. E. P., Yu, I. P. L., Huang, C-C. F., Morova, T., Altıntaş, U. B., Giambartolomei, C., Seo, J. H., Baca, S. C., Carneiro, I., Emberly, E., Pasaniuc, B., Jerónimo, C., Henrique, R., Freedman, M. L., Wessels, L. F. A., Lack, N. A., & 2 others, 30 Nov 2022, In: Nature Communications. 13, 1, 16 p., 7367.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Citation (Scopus)5 Downloads (Pure) -
Genetic determinants of chromatin reveal prostate cancer risk mediated by context-dependent gene regulation
Baca, S. C., Singler, C., Zacharia, S., Seo, J. H., Morova, T., Hach, F., Ding, Y., Schwarz, T., Huang, C. C. F., Anderson, J., Fay, A. P., Kalita, C., Groha, S., Pomerantz, M. M., Wang, V., Linder, S., Sweeney, C. J., Zwart, W., Lack, N. A., Pasaniuc, B., & 3 others, Sep 2022, In: Nature Genetics. 54, 9, p. 1364-1375 12 p.Research output: Contribution to journal › Article › Academic › peer-review
2 Citations (Scopus) -
Homing in on a Moving Target: Androgen Receptor Cistromic Plasticity in Prostate Cancer
Eickhoff, N., Bergman, A. M. & Zwart, W., 1 Nov 2022, In: Endocrinology (United States). 163, 11, 10 p., bqac153.Research output: Contribution to journal › Review article › peer-review
Datasets
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Functional mapping of androgen receptor enhancer activity
Zwart, W. T. (Creator), Linder, S. (Creator), Huang, C. F. (Creator), Le Bihan, S. (Contributor), Hach, F. (Contributor), Altintas, U. B. (Creator), Lack, N. A. (Creator), Ozturan, D. (Contributor), Collins, C. (Creator), Gokbayrak, B. (Contributor), Hoogstraat, M. (Creator), Saffarzadeh, M. (Contributor), Sar, F. (Creator), Bergman, A. M. (Creator), Stelloo, S. (Creator), Lingadahalli, S. (Contributor), Gleave, M. E. (Creator), van der Poel, H. (Contributor), Morova, T. (Contributor), McConeghy, B. (Creator), Hu, E. (Creator), Yu, I. P. L. (Creator), Feng, F. Y. (Creator) & Emberly, E. (Creator), Figshare, 12 May 2021
DOI: 10.6084/m9.figshare.c.5421005
Dataset
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Additional file 3 of Functional mapping of androgen receptor enhancer activity
Bergman, A. M. (Creator), Huang, C. F. (Creator), Linder, S. (Creator), Hoogstraat, M. (Creator), Altintas, U. B. (Creator), Lack, N. A. (Creator), van der Poel, H. (Contributor), Hach, F. (Contributor), Emberly, E. (Creator), Hu, E. (Creator), Yu, I. P. L. (Creator), Feng, F. Y. (Creator), McConeghy, B. (Creator), Morova, T. (Contributor), Sar, F. (Creator), Gleave, M. E. (Creator), Collins, C. (Creator), Saffarzadeh, M. (Contributor), Lingadahalli, S. (Contributor), Le Bihan, S. (Contributor), Ozturan, D. (Contributor), Zwart, W. T. (Creator), Stelloo, S. (Creator) & Gokbayrak, B. (Contributor), Figshare, 12 May 2021
DOI: 10.6084/m9.figshare.14576603
Dataset
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Additional file 4 of Androgen receptor reprogramming demarcates prognostic, context-dependent gene sets in primary and metastatic prostate cancer
Severson, T. (Creator), Qiu, X. (Creator), Alshalalfa, M. (Creator), Sjöström, M. (Creator), Quigley, D. (Creator), Bergman, A. (Creator), Long, H. (Creator), Feng, F. (Creator), Freedman, M. L. (Creator), Zwart, W. T. (Creator) & Pomerantz, M. M. (Creator), Figshare, 5 May 2022
DOI: 10.6084/m9.figshare.19711181
Dataset
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Androgen receptor reprogramming demarcates prognostic, context-dependent gene sets in primary and metastatic prostate cancer
Severson, T. (Creator), Qiu, X. (Creator), Alshalalfa, M. (Creator), Sjöström, M. (Creator), Quigley, D. (Creator), Bergman, A. (Creator), Long, H. (Creator), Feng, F. (Creator), Freedman, M. L. (Creator), Zwart, W. T. (Creator) & Pomerantz, M. M. (Creator), Figshare, 5 May 2022
DOI: 10.6084/m9.figshare.c.5980409
Dataset
Press / Media
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14 research teams can get started thanks to support KWF Dutch Cancer Society 20-12-2022
20/12/22
1 item of Media coverage
Press/Media: Expert Comment
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Researchers at Dana-Farber Cancer Institute Target Prostate Cancer (Androgen Receptor Reprogramming Demarcates Prognostic, Context-dependent Gene Sets In Primary and Metastatic Prostate Cancer)
2/12/22
1 item of Media coverage
Press/Media: Expert Comment
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Prof. dr. Dr Wilbert Zwart on cancer research: ‘A marathon at sprint speed’
6/09/22
1 item of Media coverage
Press/Media: Expert Comment
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a new discovery could greatly advance research
24/07/22
1 item of Media coverage
Press/Media: Expert Comment
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Prostate cancer hijacks tumor cell biorhythm to evade hormone therapy
27/06/22 → 4/07/22
6 items of Media coverage
Press/Media: Expert Comment