• 15 Citations
20182019
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Nederlands Kanker Instituut - AVL

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Research Output 2018 2019

  • 15 Citations
  • 9 Article
  • 1 Inaugural speech
  • 1 Phd Thesis 2 (Research NOT TU/e / Graduation TU/e)

A CRISPR-Cas9 screen identifies essential CTCF anchor sites for estrogen receptor-driven breast cancer cell proliferation

Korkmaz, G., Manber, Z., Lopes, R., Prekovic, S., Schuurman, K., Kim, Y., Teunissen, H., Flach, K., Wit, E. D., Galli, G. G., Zwart, W., Elkon, R. & Agami, R., 10 Oct 2019, In : Nucleic Acids Research. 47, 18, p. 9557-9572 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Clustered Regularly Interspaced Short Palindromic Repeats
Estrogen Receptor alpha
Estrogen Receptors
Cell Proliferation
Breast Neoplasms

Androgen receptor genomics for patient stratification: from biomarker discovery to mechanisms

Stelloo, S., 1 Jul 2019, Eindhoven: Technische Universiteit Eindhoven. 291 p.

Research output: ThesisPhd Thesis 2 (Research NOT TU/e / Graduation TU/e)Academic

2 Citations (Scopus)

CHD1 loss alters AR binding at lineage-specific enhancers and modulates distinct transcriptional programs to drive prostate tumorigenesis

Augello, M. A., Liu, D., Deonarine, L. D., Robinson, B. D., Huang, D., Stelloo, S., Blattner, M., Doane, A. S., Wong, E. W. P., Chen, Y., Rubin, M. A., Beltran, H., Elemento, O., Bergman, A. M., Zwart, W., Sboner, A., Dephoure, N. & Barbieri, C. E., 15 Apr 2019, In : Cancer Cell. 35, 4, p. 603-617

Research output: Contribution to journalArticleAcademicpeer-review

Androgen Receptors
Prostate
Carcinogenesis
Neoplasms
Prostatic Neoplasms
1 Citation (Scopus)

Frequent clonal relations between metastases and non-index prostate cancer lesions

Kneppers, J., Krijgsman, O., Melis, M., de Jong, J., Peeper, D. S., Bekers, E., van der Poel, H. G., Zwart, W. T. & Bergman, A. M., 24 Jan 2019, In : JCI Insight. 4, 2, 9 p., e124756

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Prostatic Neoplasms
Neoplasm Metastasis
Lymph Nodes
Mortality
Therapeutics

GATA3 truncating mutations promote cistromic re-programming in vitro, but not mammary tumor formation in mice

Cornelissen, L. M., de Bruijn, R., Henneman, L., Kim, Y., Zwart, W. & Jonkers, J., 19 Jun 2019, In : Journal of Mammary Gland Biology and Neoplasia.

Research output: Contribution to journalArticleAcademicpeer-review

Human Mammary Glands
Breast Neoplasms
Mutation
GATA3 Transcription Factor
Zinc Fingers

Press / Media

2 million euros for cancer research Netherlands Cancer Institute

Wilbert Zwart

3/07/19

1 item of media coverage

Press/Media: Expert Comment

Highway to help scientific findings to clinic

Wilbert Zwart

7/05/19

1 item of media coverage

Press/Media: Expert Comment

Wilbert Zwart receives ASPIRE award for drug test on 3D printed matrix

Wilbert Zwart

12/03/19

1 item of media coverage

Press/Media: Expert Comment

New subtypes of prostate cancer discovered

Wilbert Zwart

23/11/18

1 item of media coverage

Press/Media: Expert Comment

How do hormones affect tumor DNA in men with...

Wilbert Zwart

14/02/18

1 item of media coverage

Press/Media: Expert Comment