• 1193 Citations

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Personal profile

Research profile

Volkher Scharnhorst is part-time professor of Clinical Chemistry with the research group Chemical Biology at the department of Biomedical Engineering of Eindhoven University of Technology. His research focuses on the use of biomarkers in diagnosing and monitoring disease, with an emphasis on the improvement of analytical techniques and interpretation of test results.

In his profession as a clinical chemist Scharnhorst is committed to translating the analysis results from the laboratory into information that is of relevance to doctors in their treatment of patients. His areas of focus here are general laboratory medicine, diagnostics of blood diseases and research into biomarkers of cardiovascular diseases. Scharnhorst has performed much clinical research into the diagnosis of disorders of the cardiovascular system.

Academic background

Volkher Scharnhorst obtained his MSc in Biology at Leiden University where in 2000 he received his PhD at the department of Medical Biochemistry, for research on ‘W1 proteins and their functions in growth and differentiation’. He then became a resident in clinical chemistry at Máxima Medical Centre in Veldhoven. During his time as resident, he became lecturer chemical pathology at the Fontys Hogeschool in Eindhoven. In 2004, he received admission to the registry of clinical chemists after which he became a clinical chemist at Atrium Medical Centre in Heerlen (now Zuyderland hospital). In 2006, he continued his career at the Catharina Hospital in Eindhoven. In 2007, he was appointed member of the Medical Ethics Board (METC) and became head of the clinical laboratory of Catharina Hospital. In 2012, Eindhoven University of Technology installed him as lecturer and in 2014 as part-time Professor in Clinical Chemistry at the department of Biomedical Engineering, research group Chemical Biology.

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Research Output

Assessment of exercise-induced changes in von Willebrand factor as a marker of severity of aortic stenosis

Zelis, J. M., Zimmermann, F. M., Andriessen, F. P. J., Houthuizen, P., van de Ven, J., Leuverman, J., Johnson, N. P., Pijls, N. H. J., Scharnhorst, V., van 't Veer, M. & Tonino, P. A. L., 4 Mar 2020, In : Open Heart. 7, 1, 6 p., e001138.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
  • 8 Downloads (Pure)

    Metabolic Health Index (MHI): assessment of comorbidity in bariatric patients based on biomarkers

    van Loon, S. L. M., Deneer, R., Nienhuijs, S. W., Wilbik, A., Kaymak, U., van Riel, N., Scharnhorst, V. & Boer, A-K., 1 Feb 2020, In : Obesity Surgery. 30, 2, p. 714-724 11 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  • A multicenter evaluation of a point of care CRP Test

    Scharnhorst, V., Noordzij, P. G., Lutz, A., Graser, U., Püntener, D. & Alquézar-Arbé, A., 1 Sep 2019, In : Clinical Biochemistry. 71, Sept 2019, p. 38-45 8 p.

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access
  • 1 Citation (Scopus)
    62 Downloads (Pure)

    A value proposition for trough level-based anti-TNFα drug dosing

    Scharnhorst, V., Schmitz, E. M. H., van de Kerkhof, D., Derijks, L. J. J. & Broeren, M. A. C., 1 Feb 2019, In : Clinica Chimica Acta. 489, p. 89-95 7 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  • 1 Downloads (Pure)

    Optimized (pre)analytical conditions and workflow for droplet digital PCR analysis of cell-Free DNA from patients with suspected lung carcinoma

    de Kock, R., Deiman, B., Kraaijvanger, R. & Scharnhorst, V., 1 Sep 2019, In : The Journal of Molecular Diagnostics. 21, 5, p. 895-902 8 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  • 1 Downloads (Pure)


    Clinical Chemistry

    1/09/15 → …


    Press / Media

    POC test detects myocardial infarction

    V. Scharnhorst


    1 item of Media coverage

    Press/Media: Expert Comment

    Student theses

    ABCB1 variants in association with clopidogrel response

    Author: de Kock, R., 29 Sep 2016

    Supervisor: Brunsveld, L. (Supervisor 1), Hilbers, P. (Supervisor 2), Scharnhorst, V. (Supervisor 2) & Deiman, B. (External person) (External coach)

    Student thesis: Master

    Biomarkers as predictor of quality of life in bariatric patients

    Author: Schouten, J., 31 Jan 2019

    Supervisor: Hilbers, P. (Supervisor 1), van Riel, N. (Supervisor 2), Scharnhorst, V. (Supervisor 2), van Loon, S. (Supervisor 2) & Deneer, R. (Supervisor 2)

    Student thesis: Master

    Vitamin D metabolites in hemodialysis patients: development and validation of an LC-MS/MS method

    Author: de Backer, M., 30 Nov 2015

    Supervisor: Brunsveld, L. (Supervisor 1), Prompers, J. (Supervisor 2), Scharnhorst, V. (Supervisor 2), Broeren, M. (Supervisor 2) & van Dongen, J. (Supervisor 2)

    Student thesis: Master