• 1133 Citations
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Personal profile

Research profile

Volkher Scharnhorst is part-time professor of Clinical Chemistry with the research group Chemical Biology at the department of Biomedical Engineering of Eindhoven University of Technology. His research focuses on the use of biomarkers in diagnosing and monitoring disease, with an emphasis on the improvement of analytical techniques and interpretation of test results.

In his profession as a clinical chemist Scharnhorst is committed to translating the analysis results from the laboratory into information that is of relevance to doctors in their treatment of patients. His areas of focus here are general laboratory medicine, diagnostics of blood diseases and research into biomarkers of cardiovascular diseases. Scharnhorst has performed much clinical research into the diagnosis of disorders of the cardiovascular system.

Academic background

Volkher Scharnhorst obtained his MSc in Biology at Leiden University where in 2000 he received his PhD at the department of Medical Biochemistry, for research on ‘W1 proteins and their functions in growth and differentiation’. He then became a resident in clinical chemistry at Máxima Medical Centre in Veldhoven. During his time as resident, he became lecturer chemical pathology at the Fontys Hogeschool in Eindhoven. In 2004, he received admission to the registry of clinical chemists after which he became a clinical chemist at Atrium Medical Centre in Heerlen (now Zuyderland hospital). In 2006, he continued his career at the Catharina Hospital in Eindhoven. In 2007, he was appointed member of the Medical Ethics Board (METC) and became head of the clinical laboratory of Catharina Hospital. In 2012, Eindhoven University of Technology installed him as lecturer and in 2014 as part-time Professor in Clinical Chemistry at the department of Biomedical Engineering, research group Chemical Biology.

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Research Output 1995 2020

33 Downloads (Pure)

A multicenter evaluation of a point of care CRP Test

Scharnhorst, V., Noordzij, P. G., Lutz, A., Graser, U., Püntener, D. & Alquézar-Arbé, A., 1 Sep 2019, In : Clinical Biochemistry. 71, Sept 2019, p. 38-45 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Point-of-Care Systems
C-Reactive Protein

A value proposition for trough level-based anti-TNFα drug dosing

Scharnhorst, V., Schmitz, E. M. H., van de Kerkhof, D., Derijks, L. J. J. & Broeren, M. A. C., 1 Feb 2019, In : Clinica Chimica Acta. 489, p. 89-95 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Drug Monitoring
Tumor Necrosis Factor-alpha
Pharmaceutical Preparations
Cost-Benefit Analysis

Metabolic Health Index (MHI): assessment of comorbidity in bariatric patients based on biomarkers

van Loon, S. L. M., Deneer, R., Nienhuijs, S. W., Wilbik, A., Kaymak, U., van Riel, N., Scharnhorst, V. & Boer, A-K., 14 Nov 2019, In : Obesity Surgery. 30, 2, p. 714-724

Research output: Contribution to journalArticleAcademicpeer-review

Ambulatory Surgical Procedures
1 Downloads (Pure)

Optimized (pre)analytical conditions and workflow for droplet digital PCR analysis of cell-Free DNA from patients with suspected lung carcinoma

de Kock, R., Deiman, B., Kraaijvanger, R. & Scharnhorst, V., 1 Sep 2019, In : The Journal of Molecular Diagnostics. 21, 5, p. 895-902 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Polymerase Chain Reaction

Roche Troponin T hs-STAT meets all expert opinion analytical laboratory practice recommendations for the use of the differential diagnosis of acute coronary syndrome

Geerts, N. & Scharnhorst, V., Nov 2019, In : Clinical Chemistry and Laboratory Medicine. 57, 11, p. e285-e286 2 p.

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review


Clinical Chemistry

1/09/15 → …


Press / Media

POC test detects myocardial infarction

V. Scharnhorst


1 item of Media coverage

Press/Media: Expert Comment

Student theses

ABCB1 variants in association with clopidogrel response

Author: de Kock, R., 29 Sep 2016

Supervisor: Brunsveld, L. (Supervisor 1), Hilbers, P. (Supervisor 2), Scharnhorst, V. (Supervisor 2) & Deiman, B. (External person) (External coach)

Student thesis: Master

Biomarkers as predictor of quality of life in bariatric patients

Author: Schouten, J., 31 Jan 2019

Supervisor: Hilbers, P. (Supervisor 1), van Riel, N. (Supervisor 2), Scharnhorst, V. (Supervisor 2), van Loon, S. (Supervisor 2) & Deneer, R. (Supervisor 2)

Student thesis: Master

Vitamin D metabolites in hemodialysis patients: development and validation of an LC-MS/MS method

Author: de Backer, M., 30 Nov 2015

Supervisor: Brunsveld, L. (Supervisor 1), Prompers, J. (Supervisor 2), Scharnhorst, V. (Supervisor 2), Broeren, M. (Supervisor 2) & van Dongen, J. (Supervisor 2)

Student thesis: Master