• 1124 Citations
19952019
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Personal profile

Research profile

Volkher Scharnhorst is part-time professor of Clinical Chemistry with the research group Chemical Biology at the department of Biomedical Engineering of Eindhoven University of Technology. His research focuses on the use of biomarkers in diagnosing and monitoring disease, with an emphasis on the improvement of analytical techniques and interpretation of test results.

In his profession as a clinical chemist Scharnhorst is committed to translating the analysis results from the laboratory into information that is of relevance to doctors in their treatment of patients. His areas of focus here are general laboratory medicine, diagnostics of blood diseases and research into biomarkers of cardiovascular diseases. Scharnhorst has performed much clinical research into the diagnosis of disorders of the cardiovascular system.

Academic background

Volkher Scharnhorst obtained his MSc in Biology at Leiden University where in 2000 he received his PhD at the department of Medical Biochemistry, for research on ‘W1 proteins and their functions in growth and differentiation’. He then became a resident in clinical chemistry at Máxima Medical Centre in Veldhoven. During his time as resident, he became lecturer chemical pathology at the Fontys Hogeschool in Eindhoven. In 2004, he received admission to the registry of clinical chemists after which he became a clinical chemist at Atrium Medical Centre in Heerlen (now Zuyderland hospital). In 2006, he continued his career at the Catharina Hospital in Eindhoven. In 2007, he was appointed member of the Medical Ethics Board (METC) and became head of the clinical laboratory of Catharina Hospital. In 2012, Eindhoven University of Technology installed him as lecturer and in 2014 as part-time Professor in Clinical Chemistry at the department of Biomedical Engineering, research group Chemical Biology.

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Troponin I Medicine & Life Sciences
Assays Chemical Compounds
Troponin Medicine & Life Sciences
Wilms' Tumor Genes Medicine & Life Sciences
Wilms Tumor Medicine & Life Sciences
Biosimilar Pharmaceuticals Medicine & Life Sciences
Point-of-Care Systems Medicine & Life Sciences
Blood Chemical Compounds

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Research Output 1995 2019

A value proposition for trough level-based anti-TNFα drug dosing

Scharnhorst, V., Schmitz, E. M. H., van de Kerkhof, D., Derijks, L. J. J. & Broeren, M. A. C., 1 Feb 2019, In : Clinica Chimica Acta. 489, p. 89-95 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Drug Monitoring
Pharmaceutical Preparations
Cost-Benefit Analysis
Therapeutics
Critical Pathways

Clinical performance of a new point-of-care cardiac troponin i test

Christ, M., Geier, F., Blaschke, S., Giannitsis, E., Khellaf, M., Mair, J., Pariente, D., Scharnhorst, V., Semjonow, V. & Hausfater, P., 9 Apr 2018, In : Clinical Chemistry and Laboratory Medicine. 56, 8, p. 1336-1344

Research output: Contribution to journalArticleAcademicpeer-review

Point-of-Care Systems
Troponin
Troponin I
Blood
Myocardial Infarction

Development and evaluation of protein quantitation assays for use in health care

Schmitz, E. M. H., 4 Apr 2018, Eindhoven: Technische Universiteit Eindhoven. 153 p.

Research output: ThesisPhd Thesis 1 (Research TU/e / Graduation TU/e)Academic

Open Access
File
8 Citations (Scopus)

High treatment uptake in human immunodeficiency virus/ hepatitis C virus-coinfected patients after unrestricted access to direct-acting antivirals in the Netherlands

ATHENA HIV Observational Cohort, 1 May 2018, In : Clinical Infectious Diseases. 66, 9, p. 1352-1359 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Hepacivirus
Netherlands
Antiviral Agents
HIV
Virus Diseases
Methylmalonic Acid
Vitamin B Complex
Vitamin B 12
Testing
Data Mining

Courses

Clinical Chemistry

1/09/15 → …

Course

Press / Media

POC test detects myocardial infarction

Volkher Scharnhorst

27/08/15

1 item of media coverage

Press/Media: Expert Comment

Student theses

ABCB1 variants in association with clopidogrel response

Author: de Kock, R., 29 Sep 2016

Supervisor: Brunsveld, L. (Supervisor 1), Hilbers, P. (Supervisor 2), Scharnhorst, V. (Supervisor 2) & Deiman, B. (External person) (External coach)

Student thesis: Master

Biomarkers as predictor of quality of life in bariatric patients

Author: Schouten, J., 31 Jan 2019

Supervisor: Hilbers, P. (Supervisor 1), van Riel, N. (Supervisor 2), Scharnhorst, V. (Supervisor 2), van Loon, S. (Supervisor 2) & Deneer, R. (Supervisor 2)

Student thesis: Master

Vitamin D metabolites in hemodialysis patients: development and validation of an LC-MS/MS method

Author: de Backer, M., 30 Nov 2015

Supervisor: Brunsveld, L. (Supervisor 1), Prompers, J. (Supervisor 2), Scharnhorst, V. (Supervisor 2), Broeren, M. (Supervisor 2) & van Dongen, J. (Supervisor 2)

Student thesis: Master