Sebastiaan Overeem is Full Professor in the Signal Processing Systems group (Department of Electrical Engineering). He is a clinical somnologist and a neuroscientist, holding the chair Intelligent Systems for Sleep Disorders. He focuses on the development, validation and implementation of new diagnostic methods for sleep and sleep disorders.

Overeem has a broad interest and experience in the field of sleep medicine.  One focus over the last 15 years has been on narcolepsy, including the neurophysiology of cataplexy and the biology of the hypocretin system. The hypocretin-system formed the initial connecting link to sleep in Parkinson’s disease, when it was shown that hypocretin defects are present in Parkinson’s as a cause of sleep disturbances. This work led to a research line on sleep disorders in neurodegenerative disease, which is how Overeem was first appointed researcher at Eindhoven University of Technology (TU/e).

Within the framework of the Eindhoven MedTech Innovation Center, Overeem is participating in a various research efforts aiming to improve the diagnosis of sleep disorders, by developing and validating new non-obtrusive measurement modalities. Importantly, besides objective measures, the assessement of subjective sleep experience and symptoms is an integral topic of research.

His clinical work as a sleep medicine specialist takes place at the Center for Sleep Medicine Kempenhaeghe.

Sebastiaan Overeem holds a PhD (2003) and MD (2004) from Leiden University. Part of his theis work took place at the Center for Narcolepsy Research at Stanford University. After graduating, he worked as Assistant Professor in the Department of Neurology at Radboud University Medical Center from 2005 to 2015. In 2008, he took up the position of somnologist at expertise center Kempenhaeghe. Overeem joined Eindhoven University of Technology (TU/e) as Senior Researcher in 2015 and was appointed professor in 2017.

“Technological developments in the area of sleep diagnostics are essential to improve the care for patients with sleep disorders, diseases with a tremendous impact on quality of life.”