"Computational modeling has critically advanced our understanding of growth and remodeling of engineered cardiovascular tissues."

Sandra Loerakker is an associate professor at the TU/e department of Biomedical Engineering (research group Soft Tissue Engineering and Mechanobiology). Her research focuses on modeling the mechanobiology of native and engineered tissues using integrated computational and experimental methods, in order to obtain an improved understanding of the biological mechanisms responsible for soft tissue development, homeostasis, and disease, and to translate those findings into novel therapies in the field of regenerative medicine. She primarily focuses on understanding how mechanical factors drive soft tissue growth and remodeling at different spatial and temporal scales.

Sandra Loerakker was trained in Biomedical Engineering at Eindhoven University of Technology (TU/e) where she obtained both her BSc and MSc degrees cum laude. In 2007, she started her PhD research on the etiology and early detection of deep pressure ulcers in skeletal muscle, using a combination of computational and experimental methods. She performed part of this research at Northwestern University (USA) and in collaboration with the University of Alberta (Canada). After defending her PhD thesis at TU/e in 2011, for which she received the Best Doctoral Thesis in Biomechanics Award (2012) from the European Society of Biomechanics and the Novice Investigator Award (2012) from the European Pressure Ulcer Advisory Panel, she continued as a postdoctoral researcher in heart valve biomechanics and mechanobiology. In 2015, she was appointed as assistant professor in Modeling in Mechanobiology at the TU/e department of Biomedical Engineering, focusing on understanding the mechanobiology of native and engineered tissues using integrated computational and experimental methods. From May 2016 – April 2017, supported by a Marie Curie Individual Fellowship, she was a visiting assistant professor at Stanford University (USA). Sandra was promoted to associate professor in 2019. She is the recipient of prestigious personal grants (ERC Starting Grant in 2018, Vidi grant from the Dutch Science Foundation (NWO) in 2022), and she has been elected as Best Master Teacher of the academic year 2021-2022 at TU/e. From 2019 till 2023, Sandra was also a member of the Eindhoven Young Academy of Engineering (EYAE), serving in the EYAE board (2020-2023) and as chair (2022-2023). In 2024, she was elected as new Council member of the European Society of Biomechanics.