• 1301 Citations
20062020

Research output per year

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Personal profile

Research profile

Roy van der Meel is Assistant Professor of Precision Medicine at the TU/e's Biomedical Engineering department. His research is focused on developing RNA-based nanotherapeutics to regulate the immune response in a highly precise manner.

Academic background

Roy van der Meel studied Biomedical Sciences and Drug Innovation at Utrecht University in The Netherlands where he obtained his M.Sc. degree in 2009. He then conducted his Ph.D. research at the Utrecht University Pharmaceutics Department under supervision of Wim Hennink, Gert Storm, Robbert Jan Kok and Raymond Schiffelers. Roy's research focused on developing nanomedicines to inhibit tumor growth and angiogenesis and he obtained his Ph.D. degree in 2013. After obtaining Marie Skłodowska-Curie Action funding from the European Commission and a Veni grant from the Netherlands Organization for Scientific Research, Roy conducted postdoctoral research in the labs of Raymond Schiffelers (University Medical Center Utrecht) and Pieter Cullis (University of British Columbia, Vancouver, BC, Canada). In 2019, Roy was appointed Assistant Professor of Precision Medicine at the TU/e's Biomedical Engineering department.

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Research Output

Modular lipid nanoparticle platform technology for siRNA and lipophilic prodrug delivery

van der Meel, R., Chen, S., Zaifman, J., Kulkarni, J. A., Zhang, X. R. S., Tam, Y. K., Bally, M. B., Schiffelers, R. M., Ciufolini, M. A., Cullis, P. R. & Tam, Y. Y. C., 16 Jan 2020, In : bioRxiv. 20 p.

Research output: Contribution to journalArticleAcademic

Open Access
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  • 12 Downloads (Pure)

    Nanotechnology for organ-tunable gene editing

    van der Meel, R., 6 Apr 2020, In : Nature Nanotechnology. 2 p.

    Research output: Contribution to journalEditorialAcademicpeer-review

  • Fusion-dependent formation of lipid nanoparticles containing macromolecular payloads

    Kulkarni, J. A., Witzigmann, D., Leung, J., van der Meel, R., Zaifman, J., Darjuan, M. M., Grisch-Chan, H. M., Thöny, B., Tam, Y. Y. C. & Cullis, P. R., 14 May 2019, In : Nanoscale. 11, 18, p. 9023-9031 9 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  • 8 Citations (Scopus)

    Lipid nanoparticle technology for clinical translation of siRNA therapeutics

    Kulkarni, J. A., Witzigmann, D., Chen, S., Cullis, P. R. & van der Meel, R., 17 Sep 2019, In : Accounts of Chemical Research. 52, 9, p. 2435-2444 10 p.

    Research output: Contribution to journalReview articleAcademicpeer-review

  • 3 Citations (Scopus)

    Smart cancer nanomedicine

    van der Meel, R., Sulheim, E., Shi, Y., Kiessling, F., Mulder, W. & Lammers, T., 6 Nov 2019, In : Nature Nanotechnology. 14, 11, p. 1007–1017 11 p.

    Research output: Contribution to journalReview articleAcademicpeer-review

  • 14 Citations (Scopus)
    1 Downloads (Pure)

    Prizes

  • Marie Skłodowska-Curie Action (Global Fellowship)

    Roy van der Meel (Recipient), 2 Apr 2015

    Prize: OtherFellowships & membershipsScientific

  • Activities

    • 4 Invited talk

    A modular nanocarrier platform for delivery of siRNA and lipophilic prodrugs

    Roy van der Meel (Speaker)
    5 Feb 2019

    Activity: Talk or presentation typesInvited talkScientific

    Lipid nanoparticles enabling personalized vaccines for cancer immunotherapy

    Roy van der Meel (Speaker)
    16 Jan 2019

    Activity: Talk or presentation typesInvited talkScientific

    The Flying Dutchman: Managing an MSCA research project in Canada

    Roy van der Meel (Speaker)
    5 Nov 2018

    Activity: Talk or presentation typesInvited talkProfessional

    Nucleic acid nanobiologics to regulate trained immunity

    Roy van der Meel (Speaker)
    25 Sep 2018

    Activity: Talk or presentation typesInvited talkScientific